SCHEMBL1306041

SCHEMBL1306041

C(Cc1ccccc1)=c1ccc(=CCc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.57
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
ARG2 P78540 1/20 0.43
CALM1 P0DP23 1/20 0.43
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
LOXL2 Q9Y4K0 2/20 0.39
IDO1 P14902 1/20 0.39
TP53 P04637 1/20 0.39
TRPA1 O75762 1/20 0.39
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
CASP1 P29466 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MGLL Q99685 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
CYP2A6 P11509 1/20 0.36
HTR2A P28223 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27511115 0.76 MAOB (0.39) MAOBCA1CA2ARG2TSHR
SCHEMBL21616786 0.74 CYP3A4 (0.48) ALDH1A1LOXL2HSD17B10TDP1
SCHEMBL27944851 0.74 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL1524697 0.73 MAOB (1.00) MAOBCA1CA2ARG2CALM1
SCHEMBL155055 0.73 MAOB (1.00) MAOBCA1CA2ARG2CALM1
SCHEMBL155054 0.73 MAOB (1.00) MAOBCA1CA2ARG2CALM1
SCHEMBL74275 0.73 MAOB (0.67) MAOBCA1CA2ARG2CALM1
SCHEMBL27558493 0.72 MAOB (0.74) MAOBCA1CA2ARG2CALM1
SCHEMBL7943367 0.72 MAOB (0.50) MAOBCA1CA2ARG2CALM1
SCHEMBL28664711 0.72 MAOB (0.50) MAOBCA1CA2ARG2CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12044872-B2 Method for generating alignment on top of a liquid crystal polymer material Rolic Technologies AG (CH) 2024-07-23 US disclosed
US-12012382-B2 Polymerizable liquid crystal having a carbazole core Rolic Technologies AG (CH) 2024-06-18 US disclosed
US-12006463-B2 Polymerizable liquid crystal having a quinoxaline-hydrazone core Rolic Technologies AG (CH) 2024-06-11 US disclosed
US-11952524-B2 Compositions of polymerizable liquid crystals Rolic Technologies AG (CH) 2024-04-09 US disclosed
EP-3175493-B1 ENCAPSULATION STRUCTURE FOR AN OLED DISPLAY INCORPORATING ANTIREFLECTION PROPERTIES BASF COATINGS GMBH (DE) 2024-03-06 EP disclosed
EP-3990568-B1 NEW POLYMERIZABLE LIQUID CRYSTAL HAVING A QUINOXALINE-HYDRAZONE CORE ROLIC TECH AG (CH) 2023-11-15 EP disclosed
US-11702595-B2 Polymerizable liquid crystal Rolic Technologies AG (CH) 2023-07-18 US disclosed
EP-3126883-B1 OPTICAL DEVICES WITH PATTERNED ANISOTROPY INCORPORATING PARALLAX OPTIC ROLIC TECH AG (CH) 2023-07-12 EP disclosed
US-20220228063-A1 NEW POLYMERIZABLE LIQUID CRYSTAL Rolic Technologies AG (CH) 2022-07-21 US disclosed
US-20220163853-A1 PHOTO-ALIGNABLE POSITIVE C-PLATE RETARDER Rolic Technologies AG (CH) 2022-05-26 US disclosed
EP-2094815-B1 PATTERNABLE LIQUID CRYSTAL POLYMER COMPRISING THIO-ETHER UNITS ROLIC AG (CH) 2012-06-27 EP disclosed
US-8054411-B2 Volume photo-aligned retarder ROLIC AG (CH) 2011-11-08 US disclosed
CN-102084485-A Organic Thin Film Transistor IDEMITSU KOSAN CO 2011-06-01 CN disclosed
US-20100266821-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2010-10-21 US disclosed
US-20100266814-A1 PHOTOALIGNMENT COMPOSITION ROLIC AG (CH) 2010-10-21 US disclosed
CN-101809749-A Organic thin film transistor IDEMITSU KOSAN CO 2010-08-18 CN disclosed
US-20100059709-A1 PATTERNABLE LIQUID CRYSTAL POLYMER COMPRISING THIO-ETHER UNITS ROLIC AG (CH) 2010-03-11 US disclosed
US-20100026935-A1 VOLUME PHOTO-ALIGNED RETARDER ROLIC AG (CH) 2010-02-04 US disclosed
CN-1865206-A 2,5-diphenyl-1,4-distyyl benzene derivative and its uses in electroluminescent device UNIV JILIN (CN) 2006-11-22 CN disclosed
US-6428612-B1 Hydrogen getter package assembly HUGHES ELECTRONICS CORPORATION 2002-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12012382-B2 Polymerizable liquid crystal having a carbazole core FZD7, CCL11, SGK2 MAOB 3246/4885CA1 479/4885CA2 1166/4885
US-12006463-B2 Polymerizable liquid crystal having a quinoxaline-hydrazone core AQP1, AQP4, HCN1 MAOB 1194/4885CA1 151/4885CA2 926/4885
US-20100266821-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ETV6, TERB1, VCL MAOB 4356/4885CA1 4263/4885CA2 4712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.