Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005626 | 0.91 | RORC (0.35) | RORCMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL13061115 | 0.82 | HTR2C (0.40) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL13005531 | 0.81 | NCF1 (0.39) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL13060690 | 0.77 | CALM1 (0.40) | KCNQ2ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13005588 | 0.71 | CALM1 (0.38) | RORCMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL13061127 | 0.70 | ACHE (0.39) | MEN1KMT2AL3MBTL1ALDH1A1SLC6A2 | |
| SCHEMBL13061104 | 0.69 | KDM4E (0.37) | RORCMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL13061103 | 0.69 | TSHR (0.35) | SLC6A2SLC6A4LMNATSHRCYP1A2 | |
| SCHEMBL13061087 | 0.69 | TSHR (0.40) | MEN1KMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL13005520 | 0.68 | LMNA (0.37) | RORCSLC6A2SLC6A4SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |