Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005588 | 0.86 | CALM1 (0.38) | CALM1CAMKK2PIK3CBKDM4EGAA | |
| SCHEMBL13060673 | 0.77 | CALM1 (0.50) | CALM1CAMKK2HSD17B10KDM4ELMNA | |
| SCHEMBL13060653 | 0.77 | RORC (0.35) | PIK3CBPIK3CDPIK3CAPIK3CGALOX15 | |
| SCHEMBL10039143 | 0.75 | CALM1 (0.64) | CALM1CAMKK2KDM4ELMNAALDH1A1 | |
| SCHEMBL13005540 | 0.75 | CALM1 (0.40) | CALM1CAMKK2KDM4EGAAALDH1A1 | |
| SCHEMBL13061100 | 0.73 | CALM1 (0.55) | CALM1CAMKK2KDM4EALDH1A1 | |
| SCHEMBL13061135 | 0.71 | CALM1 (0.44) | CALM1CAMKK2HSD17B10KDM4ELMNA | |
| SCHEMBL13670051 | 0.69 | MAPT (0.48) | PIK3CBPIK3CDPIK3CAPIK3CGKDM4E | |
| SCHEMBL13060700 | 0.68 | CALM1 (0.65) | CALM1CAMKK2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6509065 | 0.67 | PKM (0.60) | ALOX15HSD17B10KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |