Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 6/20 | 0.57 |
| ▸ | DRD3 | P35462 | 4/20 | 0.57 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.52 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361520 | 0.87 | DRD2 (0.72) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL21593838 | 0.85 | NCF1 (0.50) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL3633909 | 0.84 | NCF1 (0.67) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL5722525 | 0.84 | NCF1 (0.58) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL1541501 | 0.81 | NCF1 (0.63) | NCF1DRD2DRD3HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL6662186 | 0.81 | NCF1 (0.63) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL29432674 | 0.81 | HTR1A (0.58) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL7510287 | 0.81 | BRD9 (0.40) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL404338 | 0.81 | HTR1A (0.58) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL10244134 | 0.81 | PKM (0.49) | NCF1BRD9BRD4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317644-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| US-20080153843-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317644-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | NCF1 3127/4885DRD2 3634/4885DRD3 3704/4885 |
| US-20080153843-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | SULT2A1, STS, SULT1A1 | NCF1 3127/4885DRD2 3634/4885DRD3 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.