Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.84 |
| ▸ | NPC1 | O15118 | 2/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.84 |
| ▸ | MAPT | P10636 | 6/20 | 0.79 |
| ▸ | GAA | P10253 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23652963 | 0.85 | MAPT (0.79) | RAB9ANPC1POLBMAPTGAA | |
| SCHEMBL13676147 | 0.85 | RAB9A (0.62) | RAB9ANPC1POLBMAPTGAA | |
| SCHEMBL259620 | 0.84 | ALDH1A1 (0.76) | RAB9ANPC1POLBMAPTGAA | |
| Methyl Alcohol SCHEMBL4593446 | 0.84 | MAPT (0.93) | RAB9AMAPTGAAALDH1A1KMT2A | |
| SCHEMBL3061430 | 0.84 | MAPT (1.00) | RAB9AMAPTGAAKMT2AMEN1 | |
| SCHEMBL259380 | 0.83 | HDAC3 (0.68) | RAB9ANPC1POLBMAPTALDH1A1 | |
| SCHEMBL31611777 | 0.83 | HDAC3 (0.68) | RAB9ANPC1POLBMAPTALDH1A1 | |
| SCHEMBL1471759 | 0.83 | MAPT (0.77) | RAB9ANPC1MAPTGAAALDH1A1 | |
| SCHEMBL13389060 | 0.83 | MAPT (0.77) | RAB9ANPC1POLBMAPTGAA | |
| Hydrochloric Acid SCHEMBL27689202 | 0.82 | MAPT (0.96) | RAB9AMAPTGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217694-B | Method for selectively reducing carbon-carbon double bond in alpha, beta-unsaturated carbonyl compound | 五邑大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-111217694-A | method for selectively reducing carbon-carbon double bond in α, beta-unsaturated carbonyl compound | 五邑大学 | 2020-06-02 | — | — | CN | disclosed |
| EP-2220052-B1 | CYCLIC UREA INHIBITORS OF 11ß-HYDROXYSTEROID DEHYDROGENASE 1 | VITAE PHARMACEUTICALS INC (US) | 2015-03-25 | — | — | EP | disclosed |
| US-20100324045-A1 | CYCLIC UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | VITAE PHARMACEUTICALS, INC. | 2010-12-23 | — | — | US | disclosed |
| WO-2009061498-A1 | CYCLIC UREA INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1 | VITAE PHARMACEUTICALS, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324045-A1 | CYCLIC UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | HSD11B1, HSD3B1, HSD11B2 | RAB9A 3763/4885NPC1 530/4885POLB 1831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.