Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335602 | 0.78 | NR1H2 (0.50) | HDAC8NR1H2NR1H3PTPN1 | |
| SCHEMBL5335716 | 0.75 | NR1H2 (0.34) | HDAC8NR1H2NR1H3 | |
| SCHEMBL4267425 | 0.75 | NR1H2 (0.35) | NR1H2NR1H3 | |
| SCHEMBL15302725 | 0.74 | ALDH1A1 (0.34) | NR1H2NR1H3 | |
| SCHEMBL1305259 | 0.74 | FFAR1 (0.33) | — | |
| SCHEMBL1306018 | 0.71 | — | — | |
| SCHEMBL15473033 | 0.67 | HDAC8 (0.42) | HDAC8PTPN1 | |
| SCHEMBL4283966 | 0.67 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL987797 | 0.66 | ALDH1A1 (0.47) | HDAC8 | |
| SCHEMBL28574091 | 0.65 | HDAC8 (0.50) | HDAC8PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053588-B2 | organosilane compounds used as raw materials for synthesis of organosilicon polymer thin films, having a refractive-index controlling function, a light absorbing function, a light emitting function, and a charge transferring function | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2011-11-08 | — | — | US | disclosed |
| US-8053588-B2 | organosilane compounds used as raw materials for synthesis of organosilicon polymer thin films, having a refractive-index controlling function, a light absorbing function, a light emitting function, and a charge transferring function | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2011-11-08 | — | — | US | disclosed |
| US-20080227939-A1 | Organosilane compound and organosilica obtained therefrom | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20080227939-A1 | Organosilane compound and organosilica obtained therefrom | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227939-A1 | Organosilane compound and organosilica obtained therefrom | CARM1, PRMT1, PRMT8 | HDAC8 885/4885NR1H2 346/4885NR1H3 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.