Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305956 | 0.92 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1PKMLMNAKDM4E | |
| SCHEMBL1305950 | 0.92 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1PKMLMNAKDM4E | |
| SCHEMBL1306227 | 0.91 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1PKMLMNAKDM4E | |
| SCHEMBL1306230 | 0.91 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1PKMLMNAKDM4E | |
| SCHEMBL1307055 | 0.86 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1PKMGAALMNA | |
| SCHEMBL1306574 | 0.84 | TDP1 (0.46) | KDM4EMAPT | |
| SCHEMBL1305476 | 0.82 | MAPT (0.49) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1306401 | 0.81 | P2RX3 (0.58) | L3MBTL1ALDH1A1PKMLMNAKDM4E | |
| SCHEMBL1306404 | 0.81 | P2RX3 (0.58) | L3MBTL1ALDH1A1PKMLMNAKDM4E | |
| SCHEMBL1306801 | 0.81 | KDM4E (0.47) | ALDH1A1GAALMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |