Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.46 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | TSLP | Q969D9 | 14/20 | 0.46 |
| ▸ | MC4R | P32245 | 3/20 | 0.43 |
| ▸ | MC5R | P33032 | 3/20 | 0.43 |
| ▸ | MC3R | P41968 | 3/20 | 0.43 |
| ▸ | MC1R | Q01726 | 3/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13038593 | 0.87 | ITGB3 (0.53) | CHRNA7CHRNA10CHRNA9ITGB3ITGB1 | |
| SCHEMBL14274987 | 0.85 | CHRNA10 (0.55) | CHRNA7CHRNA10CHRNA9ITGB3ITGB1 | |
| SCHEMBL12146083 | 0.79 | TSLP (0.56) | TSLPMC4RMC5RMC3RMC1R | |
| SCHEMBL13038609 | 0.78 | CHRNA10 (0.55) | CHRNA7CHRNA10CHRNA9TSLPMC4R | |
| SCHEMBL13038608 | 0.77 | MC4R (0.51) | ITGB3TSLPMC4RMC5RMC3R | |
| SCHEMBL13881404 | 0.77 | MC4R (0.51) | ITGB3TSLPMC4RMC5RMC3R | |
| SCHEMBL15397365 | 0.74 | ITGB3 (0.59) | CHRNA7CHRNA10CHRNA9ITGB3ITGB1 | |
| SCHEMBL10138562 | 0.74 | ITGB3 (0.59) | CHRNA7CHRNA10CHRNA9ITGB3ITGB1 | |
| SCHEMBL13319649 | 0.70 | CTSG (0.69) | TSLPCTSG | |
| SCHEMBL12463308 | 0.70 | ITGB3 (0.57) | ITGB3ITGB1ITGAVITGA5TSLP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129581-A1 | POLYMER MICELLES CONTAINING SN-38 FOR THE TREATMENT OF CANCER | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-11 | — | — | WO | disclosed |