Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.55 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | TSLP | Q969D9 | 10/20 | 0.49 |
| ▸ | MC4R | P32245 | 7/20 | 0.48 |
| ▸ | MC5R | P33032 | 7/20 | 0.48 |
| ▸ | MC3R | P41968 | 7/20 | 0.48 |
| ▸ | MC1R | Q01726 | 7/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13038593 | 0.92 | ITGB3 (0.53) | CHRNA10CHRNA9CHRNA7TSLPMC4R | |
| SCHEMBL12146083 | 0.86 | TSLP (0.56) | TSLPMC4RMC5RMC3RMC1R | |
| SCHEMBL13074972 | 0.85 | CHRNA7 (0.46) | CHRNA10CHRNA9CHRNA7TSLPMC4R | |
| SCHEMBL15397365 | 0.84 | ITGB3 (0.59) | CHRNA10CHRNA9CHRNA7MC4RMC5R | |
| SCHEMBL10138562 | 0.84 | ITGB3 (0.59) | CHRNA10CHRNA9CHRNA7MC4RMC5R | |
| SCHEMBL13038609 | 0.83 | CHRNA10 (0.55) | CHRNA10CHRNA9CHRNA7TSLPMC4R | |
| SCHEMBL13038608 | 0.81 | MC4R (0.51) | TSLPMC4RMC5RMC3RMC1R | |
| SCHEMBL13881404 | 0.81 | MC4R (0.51) | TSLPMC4RMC5RMC3RMC1R | |
| SCHEMBL13659874 | 0.75 | MC4R (0.56) | TSLPMC4RMC5RMC3RMC1R | |
| SCHEMBL13870335 | 0.75 | MC4R (0.55) | TSLPMC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080035243-A1 | Covalent modification of metal surfaces | INTEZYNE TECHNOLOGIES (US) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080035243-A1 | Covalent modification of metal surfaces | ITGAL, ITGA1, ITGA5 | CHRNA10 2649/4885CHRNA9 3117/4885CHRNA7 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.