Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.55 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | TSLP | Q969D9 | 6/20 | 0.48 |
| ▸ | NPR1 | P16066 | 1/20 | 0.47 |
| ▸ | NPR3 | P17342 | 1/20 | 0.47 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274987 | 0.83 | CHRNA10 (0.55) | CHRNA10CHRNA9CHRNA7TSLPMC4R | |
| SCHEMBL13038593 | 0.83 | ITGB3 (0.53) | CHRNA10CHRNA9CHRNA7TSLPCTSG | |
| SCHEMBL13074972 | 0.78 | CHRNA7 (0.46) | CHRNA10CHRNA9CHRNA7TSLPCTSG | |
| SCHEMBL12146083 | 0.75 | TSLP (0.56) | TSLPCTSGMC4RMC3RMC1R | |
| SCHEMBL12407327 | 0.74 | CTSG (0.48) | TSLPCTSGMC4RMC3RMC1R | |
| SCHEMBL13430222 | 0.73 | MC4R (0.49) | TSLPCTSGMC4RMC3RMC1R | |
| SCHEMBL10138562 | 0.73 | ITGB3 (0.59) | CHRNA10CHRNA9CHRNA7MC4RMC3R | |
| SCHEMBL15397365 | 0.73 | ITGB3 (0.59) | CHRNA10CHRNA9CHRNA7MC4RMC3R | |
| SCHEMBL18972610 | 0.73 | F2RL1 (0.47) | TSLPNPR1NPR3BCL2L1BAD | |
| SCHEMBL13038608 | 0.73 | MC4R (0.51) | TSLPCTSGMC4RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278932-A1 | POLYMER MICELLES CONTAINING SN-38 FOR THE TREATMENT OF CANCER | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278932-A1 | POLYMER MICELLES CONTAINING SN-38 FOR THE TREATMENT OF CANCER | MUC1, MSN, SNX9 | CHRNA10 4528/4885CHRNA9 4223/4885CHRNA7 4014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.