Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 1/20 | 0.74 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.74 |
| ▸ | SRC | P12931 | 14/20 | 0.70 |
| ▸ | ABL1 | P00519 | 11/20 | 0.70 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.70 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.70 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.70 |
| ▸ | PRKDC | P78527 | 10/20 | 0.70 |
| ▸ | HCK | P08631 | 9/20 | 0.70 |
| ▸ | EGFR | P00533 | 9/20 | 0.70 |
| ▸ | MTOR | P42345 | 8/20 | 0.70 |
| ▸ | EPHB4 | P54760 | 8/20 | 0.70 |
| ▸ | KDR | P35968 | 8/20 | 0.70 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.70 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.56 |
| ▸ | CSK | P41240 | 1/20 | 0.56 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129615 | 0.89 | SRC (0.79) | NUDT14NUDT5SRCABL1PIK3CD | |
| SCHEMBL129862 | 0.86 | SRC (0.80) | NUDT14NUDT5SRCABL1PIK3CD | |
| SCHEMBL129505 | 0.86 | PIK3CD (0.62) | NUDT14NUDT5SRCABL1PIK3CD | |
| SCHEMBL30782445 | 0.85 | NUDT14 (0.69) | NUDT14NUDT5SRCABL1PIK3CD | |
| SCHEMBL12366 | 0.85 | NUDT14 (0.69) | NUDT14NUDT5SRCABL1PIK3CD | |
| SCHEMBL130644 | 0.85 | NUDT14 (0.70) | NUDT14NUDT5SRCABL1PIK3CD | |
| SCHEMBL130529 | 0.85 | NUDT14 (1.00) | NUDT14NUDT5SRCABL1PIK3CD | |
| SCHEMBL130643 | 0.84 | NUDT14 (0.68) | NUDT14NUDT5SRCABL1PIK3CD | |
| SCHEMBL130590 | 0.84 | SRC (0.73) | NUDT14NUDT5SRCABL1PIK3CD | |
| SCHEMBL13826003 | 0.84 | SRC (0.68) | NUDT14NUDT5SRCABL1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS AG (CH) | 2024-01-02 | — | — | US | disclosed |
| US-11858907-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS AG (CH) | 2024-01-02 | — | — | US | disclosed |
| US-20210401840-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2021-12-30 | — | — | US | disclosed |
| US-11020399-B2 | Intermediates useful in the synthesis of compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2021-06-01 | — | — | US | disclosed |
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | SABILA BIOSCIENCES LLC (US) | 2020-11-24 | — | — | US | disclosed |
| US-10322130-B2 | Substituted chromenones as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2019-06-18 | — | — | US | disclosed |
| US-20190105324-A9 | SUBSTITUTED CHROMENONES AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2019-04-11 | — | — | US | disclosed |
| US-20180110783-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2018-04-26 | — | — | US | disclosed |
| US-20180110783-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2018-04-26 | — | — | US | disclosed |
| US-9775841-B2 | Compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2017-10-03 | — | — | US | disclosed |
| US-9421209-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-23 | — | — | US | disclosed |
| US-20150320752-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2015-11-12 | — | — | US | disclosed |
| US-20150174131-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS AG (CH) | 2015-06-25 | — | — | US | disclosed |
| US-9018375-B2 | Substituted chromenes as kinase modulators | RHIZEN PHARMACEUTICALS SA (CH) | 2015-04-28 | — | — | US | disclosed |
| US-20140080827-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS SA (CH) | 2014-03-20 | — | — | US | disclosed |
| US-8642607-B2 | 4H-chromen-4-one compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2014-02-04 | — | — | US | disclosed |
| US-20120289496-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2012-11-15 | — | — | US | disclosed |
| WO-2012151525-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2012-11-08 | — | — | WO | disclosed |
| US-20120059001-A1 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2012-03-08 | — | — | US | disclosed |
| US-20110118257-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS SA (CH) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210401840-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | NUDT14 1403/4885NUDT5 2424/4885SRC 285/4885 |
| US-20150174131-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | NUDT14 1304/4885NUDT5 2607/4885SRC 314/4885 |
| US-11020399-B2 | Intermediates useful in the synthesis of compounds as modulators of protein kinases | MAP4K2, MAP3K20, MAP3K1 | NUDT14 2289/4885NUDT5 2621/4885SRC 85/4885 |
| US-20150320752-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | NUDT14 1403/4885NUDT5 2424/4885SRC 285/4885 |
| US-20120289496-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | NUDT14 1403/4885NUDT5 2424/4885SRC 285/4885 |
| US-20190105324-A9 | SUBSTITUTED CHROMENONES AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKAR2B | NUDT14 1722/4885NUDT5 3300/4885SRC 254/4885 |
| US-20180110783-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | NUDT14 1403/4885NUDT5 2424/4885SRC 285/4885 |
| US-20140080827-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | NUDT14 1304/4885NUDT5 2607/4885SRC 314/4885 |
| US-20110118257-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | NUDT14 1304/4885NUDT5 2607/4885SRC 314/4885 |
| US-10322130-B2 | Substituted chromenones as modulators of protein kinases | MAP3K1, CSNK1A1, MAP3K2 | NUDT14 3679/4885NUDT5 4104/4885SRC 90/4885 |
| US-11858907-B2 | Kinase modulators | RPS6KA1, RPS6KA2, PRKAR2A | NUDT14 2673/4885NUDT5 3615/4885SRC 110/4885 |
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | BTK, FYN, YES1 | NUDT14 4860/4885NUDT5 4862/4885SRC 13/4885 |
| US-20120059001-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | NUDT14 1304/4885NUDT5 2607/4885SRC 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.