Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748432 | 0.79 | ADH1A (0.38) | ADH1CADH1A | |
| SCHEMBL18232542 | 0.72 | — | — | |
| SCHEMBL18814247 | 0.69 | SIGMAR1 (0.32) | — | |
| SCHEMBL3724031 | 0.67 | SIGMAR1 (0.31) | — | |
| SCHEMBL12599089 | 0.67 | SIGMAR1 (0.31) | — | |
| SCHEMBL3724030 | 0.67 | SIGMAR1 (0.31) | — | |
| SCHEMBL1425939 | 0.67 | — | — | |
| SCHEMBL14533780 | 0.67 | — | — | |
| SCHEMBL3731893 | 0.67 | SIGMAR1 (0.31) | — | |
| SCHEMBL22659191 | 0.66 | YTHDC1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825155-B2 | Oxindole derivative as feeding control agent | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090131398-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131398-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | GPR119, OXTR, CCKAR | ADH1C 92/4885ADH1A 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.