Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 7/20 | 0.46 |
| ▸ | NOS3 | P29474 | 6/20 | 0.46 |
| ▸ | NOS2 | P35228 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20173404 | 0.82 | CYP2C9 (0.49) | ALDH1A1NOS1NOS3NOS2CYP2C9 | |
| SCHEMBL11733750 | 0.79 | NOS1 (0.59) | ALDH1A1SMN1; SMN2NOS1NOS3NOS2 | |
| SCHEMBL11733757 | 0.79 | NOS1 (0.59) | ALDH1A1SMN1; SMN2NOS1NOS3NOS2 | |
| SCHEMBL24227104 | 0.78 | NOS1 (0.37) | ALDH1A1SMN1; SMN2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15159798 | 0.77 | HTR3E (0.52) | ALDH1A1SMN1; SMN2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15153262 | 0.77 | HTR3E (0.52) | ALDH1A1SMN1; SMN2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20175858 | 0.77 | ADRA2A (0.49) | ALDH1A1SMN1; SMN2NOS1NOS3NOS2 | |
| SCHEMBL7260907 | 0.74 | NOS1 (0.56) | ALDH1A1NOS1NOS3NOS2TSHR | |
| SCHEMBL7260909 | 0.74 | NOS1 (0.56) | ALDH1A1NOS1NOS3NOS2TSHR | |
| SCHEMBL10341822 | 0.71 | NOS1 (0.50) | ALDH1A1NOS1NOS3NOS2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283385-B2 | Emulsion polymerization; oil industry | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-10-09 | — | — | US | disclosed |
| US-20080197084-A1 | Reversibly switchable surfactants and methods of use thereof | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080197084-A1 | Reversibly switchable surfactants and methods of use thereof | SGMS1, SGMS2, HDHD5 | ALDH1A1 3854/4885SMN1; SMN2 1597/4885GRIN2D 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.