Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379654 | 0.86 | SIGMAR1 (0.46) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL11798244 | 0.84 | MAOA (0.50) | HTR2AMAOAMAOBSIGMAR1 | |
| SCHEMBL13086440 | 0.82 | SIGMAR1 (0.50) | MAOAMAOBSIGMAR1 | |
| SCHEMBL14781559 | 0.82 | SIGMAR1 (0.50) | MAOAMAOBSIGMAR1 | |
| SCHEMBL837703 | 0.81 | TSHR (0.36) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL13448099 | 0.81 | CA1 (0.40) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL8675805 | 0.80 | PPARA (0.46) | ALDH1A1TSHR | |
| SCHEMBL22388293 | 0.79 | OPRM1 (0.33) | MAOAMAOB | |
| SCHEMBL4309885 | 0.78 | TSHR (0.35) | ALDH1A1LOXL2TSHR | |
| SCHEMBL2441612 | 0.78 | TSHR (0.35) | ALDH1A1LOXL2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102282192-B | Soluble imide skeleton resin, soluble imide skeleton resin solution composition, curable resin composition, and cured product thereof | MITSUBISHI CHEM CORP | 2014-08-06 | — | — | CN | disclosed |
| CN-102282192-A | Soluble imide skeleton resin, soluble imide skeleton resin solution composition, curable resin composition, and cured product thereof | — | 2011-12-14 | — | — | CN | disclosed |
| US-20100261914-A1 | IAP BINDING COMPOUNDS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2010-10-14 | — | — | US | disclosed |
| US-7718600-B2 | IAP binding compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718600-B2 | IAP binding compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7674825-B2 | Dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2010-03-09 | — | — | US | disclosed |
| CN-100575413-C | Modified epoxy resin composition | NISSAN CHEMICAL IND LTD | 2009-12-30 | — | — | CN | disclosed |
| CN-100417678-C | Method of modifying a fluoropolymer and articles thereby | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-10 | — | — | CN | disclosed |
| US-20080058314-A1 | Novel dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT | 2008-03-06 | — | — | US | disclosed |
| US-20070032437-A1 | that bind cellular inhibitor of apoptosis proteins; drug design and development for diagnosis, prevention and treatment of cell proliferative disease; anticarcinogenic agents | THE TRUSTEES OF PRINCETON UNIVERSITY | 2007-02-08 | — | — | US | disclosed |
| US-20070032437-A1 | that bind cellular inhibitor of apoptosis proteins; drug design and development for diagnosis, prevention and treatment of cell proliferative disease; anticarcinogenic agents | THE TRUSTEES OF PRINCETON UNIVERSITY | 2007-02-08 | — | — | US | disclosed |
| CN-1643053-A | Thermoplastic resin composition and method for improving appearance | GEN ELECTRIC (US) | 2005-07-20 | — | — | CN | disclosed |
| CN-1026112-C | Process of preparing hydroxyalkylxanthines and medicines containing them and uses thereof | HOECHST AG (DE) | 1994-10-05 | — | — | CN | disclosed |
| CN-86105835-A | Preparation method of tertiary hydroxyalkyl xanthines, medicine containing tertiary hydroxyalkyl xanthines and application thereof | — | 1987-01-14 | — | — | CN | disclosed |
| CN-85101353-A | Preparation has the method for the pyridine-2-ether or the pyridine-2-sulfide compound of nitrogenous alicyclic ring | — | 1986-10-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058314-A1 | Novel dicarboxylic acid derivatives with pharmaceutical properties | PC, GOT2, SDHA | ALDH1A1 302/4885HPGD 394/4885ALOX15 1649/4885 |
| US-20070032437-A1 | that bind cellular inhibitor of apoptosis proteins; drug design and development for diagnosis, prevention and treatment of cell proliferative disease; anticarcinogenic agents | BIRC3, API5, BID | ALDH1A1 4507/4885HPGD 2557/4885ALOX15 4491/4885 |
| US-20100261914-A1 | IAP BINDING COMPOUNDS | BIRC3, BIRC5, BIRC2 | ALDH1A1 4654/4885HPGD 2355/4885ALOX15 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.