SCHEMBL13089115

SCHEMBL13089115

C[Si](C)(C)C[Si](C)(C)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.39
LTA4H P09960 4/20 0.36
TSHR P16473 1/20 0.36
KCNA3 P22001 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HTR1B P28222 2/20 0.33
KCNH2 Q12809 1/20 0.33
LMNA P02545 1/20 0.33
HTR1D P28221 1/20 0.33
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710740 0.91 CA4 (0.42) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL13089259 0.82 CA4 (0.39) CA4LTA4HTSHRKCNA3SMN1; SMN2
SCHEMBL707221 0.81 CA4 (0.42) CA4LTA4HTSHRKCNA3L3MBTL1
SCHEMBL13089513 0.80 CA4 (0.37) CA4LTA4HTSHRKCNA3SMN1; SMN2
SCHEMBL19816761 0.79 LTA4H (0.40) CA4LTA4HTSHRKCNA3SMN1; SMN2
SCHEMBL19901744 0.78 CA4 (0.37) CA4LTA4HTSHRKCNA3
SCHEMBL13089178 0.78 KCNA3 (0.34) CA4LTA4HTSHRKCNA3SMN1; SMN2
SCHEMBL13089242 0.78 LMNA (0.36) CA4LTA4HTSHRKCNA3LMNA
SCHEMBL23930415 0.77 ALDH1A1 (0.41) CA4LTA4HTSHRKCNA3KCNH2
SCHEMBL706868 0.77 KCNA3 (0.41) CA4LTA4HTSHRKCNA3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100261925-A1 METHOD FOR PRODUCING SILICON COMPOUND JSR CORPORATION (JP) 2010-10-14 US disclosed
US-20100174103-A1 MATERIAL FOR FORMING SILICON-CONTAINING FILM, AND SILICON-CONTAINING INSULATING FILM AND METHOD FOR FORMING THE SAME JSR CORPORATION (JP) 2010-07-08 US disclosed
US-20100140754-A1 FILM-FORMING MATERIAL, SILICON-CONTAINING INSULATING FILM AND METHOD FOR FORMING THE SAME JSR CORPORATION (JP) 2010-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100140754-A1 FILM-FORMING MATERIAL, SILICON-CONTAINING INSULATING FILM AND METHOD FOR FORMING THE SAME RIF1, SAT1, SUV39H2 CA4 1047/4885LTA4H 2642/4885TSHR 3195/4885
US-20100261925-A1 METHOD FOR PRODUCING SILICON COMPOUND GMNN, GEMIN5, SEPTIN7 CA4 147/4885LTA4H 2152/4885TSHR 4191/4885
US-20100174103-A1 MATERIAL FOR FORMING SILICON-CONTAINING FILM, AND SILICON-CONTAINING INSULATING FILM AND METHOD FOR FORMING THE SAME PROX1, PYM1, SHROOM3 CA4 1535/4885LTA4H 3314/4885TSHR 3577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.