Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CBX7 | O95931 | 1/20 | 0.42 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456813 | 0.87 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1ATMHTT | |
| SCHEMBL19419476 | 0.80 | HTT (0.57) | ALDH1A1KMT2AMEN1ATMHTT | |
| SCHEMBL19419479 | 0.77 | HTT (0.57) | ALDH1A1KMT2AMEN1ATMHTT | |
| SCHEMBL2833221 | 0.75 | L3MBTL3 (0.59) | ALDH1A1KMT2AMEN1ATMHTT | |
| SCHEMBL2832797 | 0.73 | KMT2A (0.52) | ALDH1A1KMT2AMEN1ATMHTT | |
| SCHEMBL21475151 | 0.73 | L3MBTL3 (0.60) | ALDH1A1KDM4EL3MBTL3L3MBTL1 | |
| SCHEMBL2832012 | 0.72 | ACHE (0.64) | ALDH1A1KMT2AMEN1CYP2D6CYP2C19 | |
| SCHEMBL3765286 | 0.72 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1ATMHTT | |
| SCHEMBL3780606 | 0.72 | HTT (0.57) | ALDH1A1KMT2AMEN1ATMHTT | |
| SCHEMBL2830376 | 0.71 | KMT2A (0.59) | ALDH1A1KMT2AMEN1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243776-A1 | Substituted piperidines and their use for the treatment of diseases related to the histamine H3 receptor | High Point Pharmaceuticals, LLC (US) | 2010-10-27 | — | — | EP | disclosed |