Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13408045 | 0.86 | MEN1 (0.69) | MEN1KMT2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL56319 | 0.81 | LOX (0.57) | MEN1KMT2AALDH1A1TSHRLOX | |
| SCHEMBL13604236 | 0.81 | KMT2A (0.71) | MEN1KMT2AALDH1A1LOXSIGMAR1 | |
| SCHEMBL14476103 | 0.79 | MEN1 (0.73) | MEN1KMT2AALDH1A1LOXSIGMAR1 | |
| SCHEMBL2854997 | 0.79 | SIGMAR1 (0.59) | TSHRLMNASIGMAR1L3MBTL1 | |
| SCHEMBL4632689 | 0.79 | CARM1 (0.53) | MEN1KMT2ALMNACA1CA2 | |
| SCHEMBL2850490 | 0.77 | L3MBTL1 (0.58) | TSHRLMNASIGMAR1L3MBTL1 | |
| SCHEMBL5431476 | 0.75 | SIGMAR1 (0.59) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL264656 | 0.73 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL29656296 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114945-B1 | PTERIDINONE DERIVATIVES AS PI3-KINASES INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2010-10-20 | — | — | EP | disclosed |