Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3646756 | 0.89 | IKBKB (0.49) | CHRNB2CHRNA4 | |
| SCHEMBL614050 | 0.88 | HTR2C (0.60) | HTR2CSLC18A3SIGMAR1 | |
| Bromide SCHEMBL566685 | 0.87 | IKBKB (0.48) | CHRNB2CHRNA4 | |
| Bromide SCHEMBL6921806 | 0.86 | HTR2C (0.58) | HTR2CSLC18A3SIGMAR1 | |
| SCHEMBL22608987 | 0.84 | CHRNB2 (0.47) | CHRNB2CHRNA4HTR2C | |
| SCHEMBL28533805 | 0.82 | HTR2C (0.57) | HTR2CCHRNB4CHRNA3SLC18A3SIGMAR1 | |
| SCHEMBL5839494 | 0.77 | HTR2C (0.47) | HTR2CCHRNB4CHRNA3SLC18A3SIGMAR1 | |
| SCHEMBL29890520 | 0.77 | HTR2C (0.79) | HTR2C | |
| SCHEMBL22928263 | 0.77 | HTR3A (0.52) | HTR2CCHRNB4CHRNA3SLC18A3SIGMAR1 | |
| SCHEMBL29698867 | 0.77 | HTR1A (0.50) | CHRNB2CHRNA4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565697-B | A kind of lysosome positioning fluorescence probe, preparation method and the application in near-infrared ratio test arginine | 郑州大学 | 2019-02-26 | — | — | CN | claimed |
| CN-106565697-A | Lysosome positioning fluorescence probe, preparation method, and application in arginine detection in near infrared ratio | 郑州大学 | 2017-04-19 | — | — | CN | claimed |
| EP-0853079-B1 | Production of keto acids | CIBA SC HOLDING AG (CH) | 2002-06-05 | — | — | EP | claimed |
| CN-115417751-A | Method for hydroxylation of benzene ring C-H phenol | 中山大学 | 2022-12-02 | — | — | CN | disclosed |
| CN-107037018-B | A kind of application of the lysosome positioning fluorescence probe in near-infrared ratio test hydrazine | 郑州大学 | 2019-07-30 | — | — | CN | disclosed |
| CN-106947467-B | It is a kind of to detect arginic up-conversion luminescence nanosensor material and the application in arginine detection | 郑州大学 | 2019-07-05 | — | — | CN | disclosed |
| CN-106565697-B | A kind of lysosome positioning fluorescence probe, preparation method and the application in near-infrared ratio test arginine | 郑州大学 | 2019-02-26 | — | — | CN | disclosed |
| CN-107037018-A | A kind of application of lysosome positioning fluorescence probe in near-infrared ratio test hydrazine | 郑州大学 | 2017-08-11 | — | — | CN | disclosed |
| CN-106947467-A | It is a kind of to detect arginic up-conversion luminescence nanosensor material and the application in arginine detection | 郑州大学 | 2017-07-14 | — | — | CN | disclosed |
| CN-106565697-A | Lysosome positioning fluorescence probe, preparation method, and application in arginine detection in near infrared ratio | 郑州大学 | 2017-04-19 | — | — | CN | disclosed |
| US-20110207709-A1 | MODULATORS OF SEROTONIN RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2011-08-25 | — | — | US | disclosed |
| WO-2004069256-A1 | 2-CYANOPYRROLOPYRIMIDINES AND PHARMACEUTICAL USES THEREOF | NOVARTIS AG (CH) | 2004-08-19 | — | — | WO | disclosed |
| US-6713622-B1 | CONTACTING A 4,7-DICHLORORHODAMINE DYE COMPRISING A LINKING GROUP WITH A POLYNUCLEOTIDE COMPRISING A TERMINAL FUNCTIONALITY COMPLEMENTARY TO THE LINKING GROUP | APPLERA CORPORATION | 2004-03-30 | — | — | US | disclosed |
| EP-1386946-A1 | 4,7-dichlororhodamine dyes useful as molecular probes | Applera Corporation (US) | 2004-02-04 | — | — | EP | disclosed |
| US-20030008874-A1 | 1,3 disubstituted pyrrolidines as alpha -2- adrenoceptor antagonists | NOVARTIS AG (CH) | 2003-01-09 | — | — | US | disclosed |
| EP-1257547-A1 | 1,3-DISUBSTITUTED PYRROLIDINES AS ALPHA-2-ADRENOCEPTOR ANTAGONISTS | Novartis AG (CH) | 2002-11-20 | — | — | EP | disclosed |
| EP-1165694-A1 | 4,7-DICHLORORHODAMINE DYES USEFUL AS MOLECULAR PROBES | PE Corporation (NY) (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001055132-A1 | 1,3-DISUBSTITUTED PYRROLIDINES AS ALPHA-2-ADRENOCEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2001-08-02 | — | — | WO | disclosed |
| WO-2000058406-A1 | 4,7-DICHLORORHODAMINE DYES USEFUL AS MOLECULAR PROBES | PE CORPORATION (NY) (US) | 2000-10-05 | — | — | WO | disclosed |
| US-6080852-A | FLUORESCENT DYES WITH NARROWER EMISSION SPECTRA AND WHICH ARE SHIFTED TO THE RED; FOR USE IN DIDEOXYNUCLEOTIDE SEQUENCING | THE PERKIN-ELMER CORPORATION (US) | 2000-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008874-A1 | 1,3 disubstituted pyrrolidines as alpha -2- adrenoceptor antagonists | ADRB2, ADRB1, ADRA1A | CHRNB2 43/4885CHRNA4 51/4885HTR2C 248/4885 |
| US-20110207709-A1 | MODULATORS OF SEROTONIN RECEPTOR | HTR1A, HTR6, HTR2A | CHRNB2 166/4885CHRNA4 207/4885HTR2C 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.