Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.59 |
| ▸ | CCR5 | P51681 | 1/20 | 0.59 |
| ▸ | CCR8 | P51685 | 1/20 | 0.59 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.53 |
| ▸ | METAP2 | P50579 | 2/20 | 0.47 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491437 | 0.79 | — | — | |
| SCHEMBL27905803 | 0.77 | ASIC3 (0.48) | NISCHMETAP2MTORADKALDH1A1 | |
| SCHEMBL19260909 | 0.77 | ADRA2A (0.47) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL21348456 | 0.77 | NOS3 (0.46) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL4257850 | 0.77 | CCR1 (0.63) | CCR1CCR5CCR8NISCHMTOR | |
| SCHEMBL181893 | 0.76 | CCR1 (1.00) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL29397106 | 0.76 | CCR1 (1.00) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL29639764 | 0.74 | CCR1 (0.55) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL15664136 | 0.74 | CCR1 (0.94) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL6820765 | 0.74 | CCR1 (0.94) | CCR1CCR5CCR8METAP2UHRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9953768-B2 | Metal-complex dye, photoelectric conversion element, dye-sensitized solar cell, and dye solution containing metal-complex dye | FUJIFILM CORPORATION (JP) | 2018-04-24 | — | — | US | disclosed |
| US-20160012977-A1 | METAL-COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, AND DYE SOLUTION CONTAINING METAL-COMPLEX DYE | FUJIFILM CORPORATION (JP) | 2016-01-14 | — | — | US | disclosed |
| US-9087642-B2 | Photoelectric conversion element, photoelectrochemical cell, and metal complex dye used therein | FUJIFILM CORPORATION (JP) | 2015-07-21 | — | — | US | disclosed |
| US-20140209172-A1 | PHOTOELECTRIC CONVERSION ELEMENT, PHOTOELECTROCHEMICAL CELL, AND METAL COMPLEX DYE USED THEREIN | FUJIFILM CORPORATION (JP) | 2014-07-31 | — | — | US | disclosed |
| US-20100256375-A1 | SUBSTITUTED BENZIMIDAZOLES AND METHODS OF PREPARATION | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2010-10-07 | — | — | US | disclosed |
| US-20100234394-A1 | SUBSTITUTED BENZIMIDAZOLES AND METHODS OF THEIR USE | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2010-09-16 | — | — | US | disclosed |
| US-7767820-B2 | Substituted benzimidazoles and methods of preparation | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-7732465-B2 | Substituted benzimidazoles and methods of their use | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-20090170904-A1 | Substituted benzimidazoles and methods of their use | NOVARTIS AG | 2009-07-02 | — | — | US | disclosed |
| US-7482367-B2 | Substituted benzimidazoles and methods of their use | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20080287682-A1 | Substituted benzimidazoles and methods of preparation | NOVARTIS AG | 2008-11-20 | — | — | US | disclosed |
| US-20070161680-A1 | Substituted benzimidazoles and methods of their use | NOVARTIS AG | 2007-07-12 | — | — | US | disclosed |
| US-20070049622-A1 | Substituted benzimidazoles and methods of preparation | NOVARTIS AG | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049622-A1 | Substituted benzimidazoles and methods of preparation | ABL1, CDK2, KIT | CCR1 2860/4885CCR5 3022/4885CCR8 3057/4885 |
| US-20070161680-A1 | Substituted benzimidazoles and methods of their use | BRAF, DSTYK, CHEK2 | CCR1 4167/4885CCR5 4250/4885CCR8 3951/4885 |
| US-20100256375-A1 | SUBSTITUTED BENZIMIDAZOLES AND METHODS OF PREPARATION | ABL1, CDK2, KIT | CCR1 2860/4885CCR5 3022/4885CCR8 3057/4885 |
| US-20100234394-A1 | SUBSTITUTED BENZIMIDAZOLES AND METHODS OF THEIR USE | BRAF, DSTYK, CHEK2 | CCR1 4167/4885CCR5 4250/4885CCR8 3951/4885 |
| US-20160012977-A1 | METAL-COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, AND DYE SOLUTION CONTAINING METAL-COMPLEX DYE | KCNN1, KCNN2, KCNN3 | CCR1 2750/4885CCR5 3922/4885CCR8 3539/4885 |
| US-20090170904-A1 | Substituted benzimidazoles and methods of their use | BRAF, DSTYK, CHEK2 | CCR1 4167/4885CCR5 4250/4885CCR8 3951/4885 |
| US-20080287682-A1 | Substituted benzimidazoles and methods of preparation | ABL1, CDK2, KIT | CCR1 2860/4885CCR5 3022/4885CCR8 3057/4885 |
| US-20140209172-A1 | PHOTOELECTRIC CONVERSION ELEMENT, PHOTOELECTROCHEMICAL CELL, AND METAL COMPLEX DYE USED THEREIN | L1CAM, CDH1, CD4 | CCR1 1176/4885CCR5 3312/4885CCR8 4251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.