Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310502 | 0.86 | ALDH1A1 (0.48) | SMN1; SMN2LMNAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1310957 | 0.85 | KMT2A (0.38) | SMN1; SMN2LMNAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1310266 | 0.81 | ALDH1A1 (0.52) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL1311374 | 0.76 | MAPT (0.45) | SMN1; SMN2LMNAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL14972766 | 0.75 | CYP1A2 (0.46) | LMNAALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL1325767 | 0.69 | ADH1B (0.34) | ADH1BADH1AADH7 | |
| SCHEMBL5221625 | 0.67 | ADH1B (0.61) | KMT2AALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL15107290 | 0.59 | CA2 (0.43) | KMT2AALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL6277988 | 0.59 | CA2 (0.61) | LMNAKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2359652 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846125-B2 | Enaminocarbonyl compounds and their use | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2014-09-30 | — | — | US | disclosed |
| EP-2391614-B1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INST CHEMII ORGANICZNEJ POLSKA AKADEMIA NAUK (PL) | 2013-05-29 | — | — | EP | disclosed |
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | TAS2R42, TAS2R41, TAS2R1 | SMN1; SMN2 991/4885LMNA 814/4885KMT2A 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.