Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 10/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.61 |
| ▸ | CCR2 | P41597 | 2/20 | 0.61 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.57 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.56 |
| ▸ | JAK2 | O60674 | 2/20 | 0.56 |
| ▸ | PRKACA | P17612 | 2/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.56 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.56 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.56 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.56 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | JAK1 | P23458 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13122184 | 0.89 | CLK2 (0.68) | ROCK2ROCK1CCR2NPC1RAB9A | |
| SCHEMBL18668974 | 0.86 | ROCK2 (0.67) | ROCK2ROCK1CCR2TRPM5AURKB | |
| SCHEMBL24137909 | 0.83 | CCNC (0.54) | ROCK2ROCK1CCR2AURKBJAK2 | |
| SCHEMBL5640400 | 0.83 | ROCK2 (0.81) | ROCK2ROCK1AURKBJAK2PRKACA | |
| SCHEMBL13122305 | 0.81 | TRPA1 (0.54) | ROCK2ROCK1TRPM5MEN1KMT2A | |
| SCHEMBL13122220 | 0.80 | ROCK1 (0.60) | ROCK2ROCK1CCR2TRPM5JAK2 | |
| SCHEMBL13122773 | 0.79 | TDO2 (0.60) | ROCK2ROCK1TRPM5JAK2NPC1 | |
| SCHEMBL5416850 | 0.78 | PAK4 (0.59) | ROCK2ROCK1TRPM5IDH1 | |
| SCHEMBL13122152 | 0.78 | TRPM5 (0.60) | ROCK2ROCK1CCR2TRPM5AURKB | |
| SCHEMBL13122260 | 0.77 | ROCK2 (0.59) | ROCK2ROCK1CCR2TRPM5AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812045-B2 | Antifungal triazole derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2010-10-12 | — | — | US | disclosed |
| US-20080194661-A1 | Antifungal Triazole Derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194661-A1 | Antifungal Triazole Derivatives | ERG28, CYP51A1, CYP3A43 | ROCK2 3079/4885ROCK1 3410/4885CCR2 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.