Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | PCNA | P12004 | 3/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12157338 | 0.95 | BACE1 (0.42) | BACE1PCNALNPEPMDM4MDM2 | |
| SCHEMBL12174043 | 0.90 | PCNA (0.41) | BACE1PCNALNPEPMDM4MDM2 | |
| SCHEMBL13123764 | 0.90 | ALDH1A1 (0.48) | BACE1PCNALNPEPMDM4MDM2 | |
| SCHEMBL31072235 | 0.90 | ALDH1A1 (0.48) | BACE1PCNALNPEPMDM4MDM2 | |
| SCHEMBL24091032 | 0.87 | ALDH1A1 (0.46) | BACE1PCNALNPEPMDM4MDM2 | |
| SCHEMBL24091040 | 0.85 | PCNA (0.54) | BACE1PCNAMDM4MDM2ALDH1A1 | |
| SCHEMBL12157341 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KMT2ATACR1TP53 | |
| SCHEMBL4408320 | 0.82 | PCNA (0.36) | PCNAALDH1A1KMT2ATACR1TP53 | |
| SCHEMBL13938296 | 0.81 | ALDH1A1 (0.46) | BACE1PCNALNPEPMDM4MDM2 | |
| SCHEMBL21884113 | 0.81 | ALDH1A1 (0.46) | BACE1PCNALNPEPMDM4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883861-B2 | Iminic monomers and polymers thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-11-11 | — | — | US | disclosed |
| US-8883861-B2 | Iminic monomers and polymers thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-11-11 | — | — | US | disclosed |
| US-8551511-B2 | Phase-separated biocompatible polymer compositions for medical uses | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-10-08 | — | — | US | disclosed |
| US-8551511-B2 | Phase-separated biocompatible polymer compositions for medical uses | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-10-08 | — | — | US | disclosed |
| US-8288590-B2 | N-substituted monomers and polymers | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-10-16 | — | — | US | disclosed |
| US-8288590-B2 | N-substituted monomers and polymers | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-10-16 | — | — | US | disclosed |
| US-20120108677-A1 | IMINIC MONOMERS AND POLYMERS THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-05-03 | — | — | US | disclosed |
| US-20120108677-A1 | IMINIC MONOMERS AND POLYMERS THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-05-03 | — | — | US | disclosed |
| US-8034365-B2 | Polymer substituted with amide or thioamide groups; vascular stents, bioreabsorbable polymers | REVA MEDICAL, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-8034365-B2 | Polymer substituted with amide or thioamide groups; vascular stents, bioreabsorbable polymers | REVA MEDICAL, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-20110086001-A1 | COMPLIANT BIOCOMPATIBLE POLYMER COMPOSITIONS FOR MEDICAL USES | RUTGERS UNIVERSITY (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086001-A1 | COMPLIANT BIOCOMPATIBLE POLYMER COMPOSITIONS FOR MEDICAL USES | RUTGERS UNIVERSITY (US) | 2011-04-14 | — | — | US | disclosed |
| US-20100228343-A1 | PHASE-SEPARATED BIOCOMPATIBLE POLYMER COMPOSITIONS FOR MEDICAL USES | RUTGERS, THE STATE UNIVERSITY (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100228343-A1 | PHASE-SEPARATED BIOCOMPATIBLE POLYMER COMPOSITIONS FOR MEDICAL USES | RUTGERS, THE STATE UNIVERSITY (US) | 2010-09-09 | — | — | US | disclosed |
| WO-2010042917-A1 | PHASE-SEPARATED BIOCOMPATIBLE POLYMER COMPOSITIONS FOR MEDICAL USES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-04-15 | — | — | WO | disclosed |
| US-20080187567-A1 | N-SUBSTITUTED MONOMERS AND POLYMERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2008-08-07 | — | — | US | disclosed |
| US-20080187567-A1 | N-SUBSTITUTED MONOMERS AND POLYMERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2008-08-07 | — | — | US | disclosed |
| WO-2008082738-A2 | N-SUBSTITUTED MONOMERS AND POLYMERS | RUTGERS, THE STATE UNIVERSITY (US) | 2008-07-10 | — | — | WO | disclosed |
| US-20080112999-A1 | N-SUBSTITUTED MONOMERS AND POLYMERS | REVA MEDICAL, INC. (US) | 2008-05-15 | — | — | US | disclosed |
| US-20080112999-A1 | N-SUBSTITUTED MONOMERS AND POLYMERS | REVA MEDICAL, INC. (US) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080187567-A1 | N-SUBSTITUTED MONOMERS AND POLYMERS | NANS, NCL, PNISR | BACE1 4614/4885PCNA 39/4885LNPEP 92/4885 |
| US-20120108677-A1 | IMINIC MONOMERS AND POLYMERS THEREOF | MIF, IGF2BP1, INMT | BACE1 4525/4885PCNA 197/4885LNPEP 2091/4885 |
| US-20110086001-A1 | COMPLIANT BIOCOMPATIBLE POLYMER COMPOSITIONS FOR MEDICAL USES | BMP2, ECPAS, PLOD3 | BACE1 4836/4885PCNA 405/4885LNPEP 388/4885 |
| US-20100228343-A1 | PHASE-SEPARATED BIOCOMPATIBLE POLYMER COMPOSITIONS FOR MEDICAL USES | BMP2, PUF60, MYADM | BACE1 4606/4885PCNA 265/4885LNPEP 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.