SCHEMBL13129265

SCHEMBL13129265

c1cc(-c2ccc3c4ccccc4c4ccccc4c3c2)c2ccsc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ERN1 O75460 2/20 0.39
ALOX5 P09917 3/20 0.39
F9 P00740 1/20 0.36
HDAC2 Q92769 1/20 0.34
HTR1A P08908 1/20 0.33
DRD2 P14416 1/20 0.33
HTR2A P28223 1/20 0.33
MCL1 Q07820 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
PRKDC P78527 3/20 0.32
XDH P47989 1/20 0.32
SLC22A12 Q96S37 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
TNKS O95271 1/20 0.32
PARP1 P09874 1/20 0.32
PARP15 Q460N3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13129269 0.80 ERN1 (0.56) ERN1HDAC2PRKDCCYP2A6
SCHEMBL769228 0.80 ADRA2A (0.44) ADRA2AADRA2BERN1ALOX5F9
SCHEMBL4315241 0.80 ADRA2A (0.49) ADRA2AADRA2BALOX5F9HTR1A
SCHEMBL10944347 0.79 ADRA2A (0.51) ADRA2AADRA2BALOX5F9HTR1A
SCHEMBL14603448 0.79 ALOX5 (0.59) ALOX5F9PRKDCTNKSTNKS2
SCHEMBL5153625 0.77 ADRA2A (0.56) ADRA2AADRA2BHTR1ADRD2HTR2A
SCHEMBL9749622 0.76 ALOX5 (0.46) ADRA2AADRA2BALOX5F9XDH
SCHEMBL23555402 0.75 ADRA2A (0.45) ADRA2AADRA2BHTR1ADRD2HTR2A
SCHEMBL28744574 0.75 ADRA2A (0.45) ADRA2AADRA2BALOX5F9HTR1A
SCHEMBL23555859 0.75 ADRA2A (0.42) ADRA2AADRA2BERN1ALOX5F9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10374171-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9705092-B2 Phosphorescent organic light emitting devices combined with hole transport material having high operating stability UNIVERSAL DISPLAY CORPORATION (US) 2017-07-11 US disclosed
US-9705092-B2 Phosphorescent organic light emitting devices combined with hole transport material having high operating stability UNIVERSAL DISPLAY CORPORATION (US) 2017-07-11 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
EP-3159333-A2 BENZO-FUSED THIOPHENE OR FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP Universal Display Corporation (US) 2017-04-26 EP disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 US disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 US disclosed
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-12-24 US disclosed
US-9153786-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-10-06 US disclosed
US-20140339518-A1 PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES COMBINED WITH HOLE TRANSPORT MATERIAL HAVING HIGH OPERATING STABILITY HODOGAYA CHEMICAL CO., LTD. (JP) 2014-11-20 US disclosed
US-20140326977-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2014-11-06 US disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 US disclosed
US-20130175510-A1 BENZO-FUSED THIOPHENE / TRIPHENYLENE HYBRID MATERIALS UNIVERSAL DISPLAY CORPORTION (US) 2013-07-11 US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group TFEB, BRD4, TEC ADRA2A 4585/4885ADRA2B 4310/4885ERN1 3410/4885
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEC ADRA2A 3301/4885ADRA2B 3309/4885ERN1 2103/4885
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEAD2 ADRA2A 4396/4885ADRA2B 4303/4885ERN1 1905/4885
US-10374171-B2 Organic electroluminescent materials and devices TPR, EED, TEAD2 ADRA2A 4396/4885ADRA2B 4303/4885ERN1 1905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.