SCHEMBL769228

SCHEMBL769228

c1cc(-c2ccc3[nH]c4ccc(-c5cccc6sccc56)cc4c3c2)c2ccsc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.44
ADRA2B P18089 1/20 0.44
ALOX5 P09917 1/20 0.34
HTR1A P08908 6/20 0.33
DRD2 P14416 6/20 0.33
HTR2A P28223 6/20 0.33
KIF11 P52732 1/20 0.33
AHR P35869 1/20 0.32
GABRA1 P14867 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRA6 Q16445 2/20 0.32
ERN1 O75460 1/20 0.32
NEK1 Q96PY6 1/20 0.32
F9 P00740 1/20 0.31
JAK2 O60674 1/20 0.31
JAK1 P23458 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13129265 0.80 ADRA2A (0.43) ADRA2AADRA2BALOX5HTR1ADRD2
SCHEMBL18805419 0.79 ERN1 (0.51) AHRERN1
SCHEMBL10944347 0.77 ADRA2A (0.51) ADRA2AADRA2BALOX5HTR1ADRD2
SCHEMBL5153625 0.74 ADRA2A (0.56) ADRA2AADRA2BHTR1ADRD2HTR2A
SCHEMBL4315241 0.73 ADRA2A (0.49) ADRA2AADRA2BALOX5HTR1ADRD2
SCHEMBL787967 0.73 ALOX5 (0.64) ALOX5KIF11AHR
SCHEMBL23555402 0.73 ADRA2A (0.45) ADRA2AADRA2BHTR1ADRD2HTR2A
SCHEMBL14828366 0.73 MCL1 (0.47) AHRTLR8TLR7GSK3B
SCHEMBL23555859 0.72 ADRA2A (0.42) ADRA2AADRA2BALOX5ERN1F9
SCHEMBL23555373 0.71 ADRA2A (0.44) ADRA2AADRA2BHTR1ADRD2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727419-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2020-07-28 US disclosed
EP-3018727-B1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO LTD (KR) 2019-09-04 EP disclosed
US-10071993-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-09-11 US disclosed
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-12-29 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
CN-105590946-A Organic light emitting display device LG DISPLAY CO LTD 2016-05-18 CN disclosed
US-20160133855-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2016-05-12 US disclosed
EP-3018727-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG Display Co., Ltd. (KR) 2016-05-11 EP disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
WO-2012039262-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL AND ORGANIC SEMICONDUCTOR MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 WO disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ADRA2A 3843/4885ADRA2B 3839/4885ALOX5 1162/4885
US-10071993-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SLC39A3, SULT1A1, NUTF2 ADRA2A 3843/4885ADRA2B 3839/4885ALOX5 1162/4885
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ADRA2A 3843/4885ADRA2B 3839/4885ALOX5 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.