SCHEMBL131560

SCHEMBL131560

ClC(Cc1ccccc1)OC(Cl)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
TAAR1 Q96RJ0 4/20 0.44
SLC6A2 P23975 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
MAOA P21397 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
CYP1A2 P05177 1/20 0.43
SLC18A2 Q05940 1/20 0.41
ANPEP P15144 1/20 0.41
CYP2D6 P10635 1/20 0.41
SRR Q9GZT4 2/20 0.41
TSHR P16473 1/20 0.40
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
PTGS1 P23219 1/20 0.40
XIAP P98170 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28400651 0.95 EPHX1 (0.44) EPHX1TAAR1SLC6A2SIGMAR1MAOA
Magnesium Chloride Anhydrous SCHEMBL28400650 0.93 EPHX1 (0.43) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL14667804 0.87 SIGMAR1 (0.48) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL935835 0.81 TAAR1 (0.46) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL8194993 0.79 EPHX1 (0.43) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL14667806 0.79 TSHR (0.46) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL14667805 0.78 TAAR1 (0.43) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL31618519 0.76 SRR (0.43) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL9118343 0.76 TAAR1 (0.42) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL8194995 0.76 SRR (0.42) EPHX1TAAR1SLC6A2SIGMAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118202009-A Ink applicator 墨水盒墨水公司 2024-06-14 CN claimed
WO-1998051659-A1 SALICYLOXY α-CARBOXY ACIDS AND PREPARATION THEREOF UNILEVER PLC (GB) 1998-11-19 WO claimed
US-20260130904-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2026-05-14 US disclosed
EP-3911640-B1 PCSK9 INHIBITORS FOR USE IN THERAPY, ESPECIALLY THE TREATMENT OF CARDIOVASCULAR DISEASE ASTRAZENECA AB (SE) 2026-05-13 EP disclosed
US-12612413-B2 Heteroaryl compounds as inhibitors of programmed necrosis pathway, composition and method using the same ACCRO BIOSCIENCE (HK) LIMITED (CN) 2026-04-28 US disclosed
US-12584120-B2 PCSK9 inhibitors and methods of use thereof ASTRAZENECA AB (SE) 2026-03-24 US disclosed
US-12552807-B2 PCSK9 inhibitors and methods of use thereof ASTRAZENECA AB (SE) 2026-02-17 US disclosed
US-20250339411-A1 GLP-1R AGONIST COMPOUND AND USE THEREOF CHONGQING PHARMACEUTICAL RES INSTITUTE CO LTD (CN) 2025-11-06 US disclosed
US-12419874-B2 GLP-1R agonist compound and use thereof CHONGQING PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) 2025-09-23 US disclosed
EP-4612156-A1 ANTI-VIRAL COMPOUNDS Aligos Therapeutics, Inc. (US) 2025-09-10 EP disclosed
EP-4605386-A1 ANTI-VIRAL COMPOUNDS Aligos Therapeutics, Inc. (US) 2025-08-27 EP disclosed
EP-0223437-A2 Aminocarbonyl renin inhibitors E.R. Squibb & Sons, Inc. (US) 1987-05-27 EP disclosed
US-4668814-A ANTIULCER AGENTS, ANTIASHMATICS, ANTICOAGULANTS THE UPJOHN COMPANY (US) 1987-05-26 US disclosed
US-4624951-A Substituted pyridazinones, pharmaceutical preparations containing these compounds, and the use thereof CIBA-GEIGY CORPORATION (US) 1986-11-25 US disclosed
EP-0159784-A1 Carbacyclin analogues THE UPJOHN COMPANY (US) 1985-10-30 EP disclosed
EP-0126506-A2 Preparation of the alkyl cyclopentane-carboxylates useful as intermediates for preparing prostaglandins CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1984-11-28 EP disclosed
EP-0094065-A2 2-Aminobenzoic acid derivatives, a process for their preparation and pharmaceutical compositions FERRER INTERNACIONAL, S.A. (ES) 1983-11-16 EP disclosed
EP-0000453-B1 PROCESS FOR THE PREPARATION OF THIENOPYRIDINE DERIVATIVES. OMNIUM FINANCIER AQUITAINE POUR L'HYGIENE ET LA SANTE - SANOFI (FR) 1980-07-23 EP disclosed
US-4198421-A ANTIARTHRITIC E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-04-15 US disclosed
EP-0000453-A1 Process for the preparation of thienopyridine derivatives. OMNIUM FINANCIER AQUITAINE POUR L'HYGIENE ET LA SANTE - SANOFI (FR) 1979-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612413-B2 Heteroaryl compounds as inhibitors of programmed necrosis pathway, composition and method using the same CASP6, CASP3, BAX EPHX1 4118/4885TAAR1 1089/4885SLC6A2 2150/4885
US-20260130904-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS EBP, SIGMAR1, EP300 EPHX1 1318/4885TAAR1 181/4885SLC6A2 477/4885
US-12552807-B2 PCSK9 inhibitors and methods of use thereof PCSK9, PCSK7, PCSK6 EPHX1 652/4885TAAR1 3523/4885SLC6A2 1359/4885
US-12584120-B2 PCSK9 inhibitors and methods of use thereof PCSK9, LDLR, PCSK7 EPHX1 3511/4885TAAR1 3228/4885SLC6A2 263/4885
US-20250339411-A1 GLP-1R AGONIST COMPOUND AND USE THEREOF GLP1R, GIPR, GPR119 EPHX1 4003/4885TAAR1 344/4885SLC6A2 467/4885
US-12419874-B2 GLP-1R agonist compound and use thereof GLP1R, GIPR, GPR119 EPHX1 4003/4885TAAR1 344/4885SLC6A2 467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.