SCHEMBL1315718

SCHEMBL1315718

CC(C)(C)OC(=O)c1ccc(-c2cncc3ccccc23)cc1[N+](=O)[O-]

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ERN1 O75460 3/20 0.52
▸ CYP11B1 P15538 11/20 0.44
▸ CYP11B2 P19099 11/20 0.44
▸ CYP2D6 P10635 2/20 0.44
▸ CYP2C9 P11712 2/20 0.44
▸ CYP2B6 P20813 2/20 0.44
▸ CYP2C19 P33261 2/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ WNT1 P04628 1/20 0.41
▸ DYRK1A Q13627 1/20 0.41
▸ PRKCZ Q05513 1/20 0.39
▸ MET P08581 1/20 0.39
▸ SLC22A12 Q96S37 2/20 0.38
▸ SERPINE1 P05121 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13206262 0.83 ERN1 (0.58) ERN1CYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL1316049 0.83 PRKCZ (0.48) ERN1CYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL12117467 0.79 MCL1 (0.42) MET
SCHEMBL4221601 0.78 ABCB1 (0.52) —
SCHEMBL1316419 0.77 ABCB1 (0.47) —
SCHEMBL12466331 0.76 L3MBTL1 (0.42) CYP11B1CYP11B2
SCHEMBL4212947 0.75 ABCG2 (0.44) ERN1CYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL1315471 0.75 NPC1 (0.43) MET
SCHEMBL1316782 0.74 TRPV1 (0.43) —
SCHEMBL2272548 0.74 ALDH1A1 (0.43) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 — — US disclosed
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 — — US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 — — US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 — — US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 ERN1 4267/4885CYP11B1 739/4885CYP11B2 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback