Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | RECQL | P46063 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | THPO | P40225 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15450382 | 0.84 | AKR1C3 (0.37) | MAPTTSHRHSD17B10EPAS1MAPK1 | |
| SCHEMBL3123515 | 0.81 | ACHE (0.40) | LMNABLMTSHRKMT2ACYP1A2 | |
| SCHEMBL16216092 | 0.79 | ADRB1 (0.61) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL16216243 | 0.79 | ADRB1 (0.61) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL19360100 | 0.75 | KDM4E (0.70) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL27339647 | 0.75 | ADRB2 (0.41) | MAPTALOX15TSHRAPEX1ADRB2 | |
| SCHEMBL11798974 | 0.74 | TYR (0.42) | KDM4ETDP1MAPTLMNAHIF1A | |
| SCHEMBL29478063 | 0.74 | ADRB1 (0.57) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL30352856 | 0.74 | ADRB1 (0.57) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL28327147 | 0.74 | ADRB1 (0.57) | ADRB1ADRA2AADRB3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8491868-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| US-8491868-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2010-09-02 | — | — | US | disclosed |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | ADRB1 7/4885ADRA2A 20/4885ADRB3 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.