Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636709 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRL3MBTL1KDM4EFDPS | |
| SCHEMBL973079 | 0.71 | ALDH1A1 (0.59) | ALDH1A1TSHRKDM4EFDPSMAPK1 | |
| SCHEMBL9375950 | 0.69 | ALDH1A1 (0.52) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL10013754 | 0.68 | MAOA (0.49) | ALDH1A1TSHRL3MBTL1KDM4EHPGD | |
| SCHEMBL14397598 | 0.67 | ALDH1A1 (0.49) | ALDH1A1TSHRL3MBTL1KDM4EFDPS | |
| SCHEMBL17859703 | 0.66 | ACHE (0.39) | ALDH1A1KDM4EMAPT | |
| SCHEMBL13893746 | 0.64 | ALDH1A1 (0.34) | ALDH1A1TSHRL3MBTL1HPGDSRC | |
| SCHEMBL111326 | 0.63 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4EFDPSMAPK1 | |
| SCHEMBL6556526 | 0.63 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4EFDPSMAPK1 | |
| SCHEMBL6850758 | 0.63 | ALDH1A1 (0.58) | ALDH1A1TSHRL3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247439-A1 | DENDRITIC NANO-ANTIOXIDANTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247439-A1 | DENDRITIC NANO-ANTIOXIDANTS | GPX1, GPX4, LPO | ALDH1A1 235/4885TSHR 4329/4885L3MBTL1 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.