Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23818606 | 1.00 | TDP1 (0.47) | TDP1ALDH1A1USP2MAPTSMN1; SMN2 | |
| SCHEMBL304203 | 0.90 | TDP1 (0.54) | TDP1ALDH1A1USP2MAPTSMN1; SMN2 | |
| SCHEMBL6131221 | 0.83 | TDP1 (0.48) | TDP1ALDH1A1USP2MAPTSMN1; SMN2 | |
| SCHEMBL10020242 | 0.81 | TDP1 (0.47) | TDP1ALDH1A1USP2MAPTSMN1; SMN2 | |
| SCHEMBL8074473 | 0.80 | ALDH1A1 (0.58) | TDP1ALDH1A1USP2MAPTSMN1; SMN2 | |
| SCHEMBL15249360 | 0.79 | TDP1 (0.45) | TDP1ALDH1A1USP2MAPTSMN1; SMN2 | |
| SCHEMBL821544 | 0.79 | TDP1 (0.45) | TDP1ALDH1A1USP2MAPTSMN1; SMN2 | |
| SCHEMBL10799810 | 0.79 | MEN1 (0.47) | TDP1ALDH1A1USP2MAPTSMN1; SMN2 | |
| SCHEMBL12156887 | 0.79 | ADRB2 (0.32) | SMN1; SMN2MEN1KMT2ALMNATSHR | |
| SCHEMBL22985141 | 0.79 | LMNA (0.50) | TDP1ALDH1A1USP2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |