SCHEMBL3706426

SCHEMBL3706426

NCCCCc1ccc(F)cc1

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.70
MAOA P21397 2/20 0.60
MAOB P27338 3/20 0.59
LOXL2 Q9Y4K0 1/20 0.54
HRH1 P35367 2/20 0.54
HTR2A P28223 2/20 0.48
AOC3 Q16853 2/20 0.47
AOC2 O75106 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21726316 0.98 TAAR1 (0.67) TAAR1MAOAMAOBLOXL2HRH1
SCHEMBL7005631 0.98 TAAR1 (0.67) TAAR1MAOAMAOBLOXL2HRH1
SCHEMBL1567051 0.98 TAAR1 (0.67) TAAR1MAOAMAOBLOXL2HRH1
SCHEMBL29263666 0.98 TAAR1 (0.67) TAAR1MAOAMAOBLOXL2HRH1
Hydrochloric Acid SCHEMBL7393435 0.98 TAAR1 (0.67) TAAR1MAOAMAOBLOXL2HRH1
SCHEMBL1319643 0.93 TAAR1 (0.73) TAAR1MAOAMAOBLOXL2HRH1
Hydrochloric Acid SCHEMBL2149447 0.91 TAAR1 (0.70) TAAR1MAOAMAOBLOXL2HTR2A
SCHEMBL10574057 0.87 TAAR1 (0.62) TAAR1MAOBLOXL2AOC3
SCHEMBL3680378 0.87 MAOA (0.75) TAAR1MAOAMAOBHRH1HTR2A
SCHEMBL10571903 0.85 TAAR1 (0.59) TAAR1MAOBLOXL2AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-06-23 US claimed
WO-2020130592-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME 서울대학교산학협력단 2020-06-25 WO claimed
CN-114950558-B Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing hydrocarbon molecule benzyl site selective oxidation by using same 陕西师范大学 2023-08-11 CN disclosed
CN-114950558-A Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing benzyl-site selective oxidation of hydrocarbon molecules by using same 陕西师范大学 2022-08-30 CN disclosed
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-06-23 US disclosed
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-06-23 US disclosed
US-20220102660-A1 DEFECT SUPPRESSED METAL HALIDE PEROVSKITE LIGHT-EMITTING MATERIAL AND LIGHT-EMITTING DIODE COMPRISING THE SAME SN DISPLAY CO., LTD. (KR) 2022-03-31 US disclosed
WO-2021125412-A1 DEFECT-SUPPRESSED METAL HALIDE PEROVSKITE LUMINESCENT MATERIAL, AND LIGHT-EMITTING DIODE COMPRISING SAME 서울대학교산학협력단 2021-06-24 WO disclosed
CN-107739371-B Tetrahydrocarbazole micromolecule organic compound, application thereof in preparing antibacterial drugs and preparation method thereof 华东师范大学 2020-08-25 CN disclosed
WO-2020130592-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME 서울대학교산학협력단 2020-06-25 WO disclosed
CN-106883224-B 1 inhibitor of nitrogen-containing benzoheterocycle class indoles amine -2,3- dioxygenase and application thereof 中国药科大学 2019-10-22 CN disclosed
US-20120122842-A1 NAMPT AND ROCK INHIBITORS ABBOTT LABORATORIES (US) 2012-05-17 US disclosed
US-7816376-B2 Cyclic amides MERCK PATENT GMBH (DE) 2010-10-19 US disclosed
US-7816376-B2 Cyclic amides MERCK PATENT GMBH (DE) 2010-10-19 US disclosed
EP-1485363-B1 CYCLIC AMIDES MERCK PATENT GMBH (DE) 2008-10-08 EP disclosed
US-5698552-A EXHIBIT PLATELET ACTIVATING FACTOR-ANTAGONISTIC ACTIVITY BOEHRINGER INGELHEIM KG (DE) 1997-12-16 US disclosed
EP-0596802-B1 Erythromycin derivatives, their process of preparation and their application as medicaments ROUSSEL UCLAF (FR) 1996-03-20 EP disclosed
EP-0596802-A1 Erythromycin derivatives, their process of preparation and their application as medicaments ROUSSEL UCLAF (FR) 1994-05-11 EP disclosed
US-5153327-A 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease E. R. SQUIBB & SONS, INC. (US) 1992-10-06 US disclosed
US-5100889-A Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor E. R. SQUIBB & SONS, INC. (US) 1992-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME HCN4, SLC46A1, FES TAAR1 4232/4885MAOA 770/4885MAOB 880/4885
US-20120122842-A1 NAMPT AND ROCK INHIBITORS NAMPT, NNMT, NME2 TAAR1 4154/4885MAOA 280/4885MAOB 279/4885
US-20220102660-A1 DEFECT SUPPRESSED METAL HALIDE PEROVSKITE LIGHT-EMITTING MATERIAL AND LIGHT-EMITTING DIODE COMPRISING THE SAME AXIN2, CRY2, PER2 TAAR1 2723/4885MAOA 3144/4885MAOB 3093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.