Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718417 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ALOX15TSHRHNF4ANR4A1 | |
| SCHEMBL29563004 | 0.83 | MYC (0.52) | ALDH1A1ALOX15POLBMYCL3MBTL1 | |
| SCHEMBL13218684 | 0.82 | TDP1 (0.41) | ALDH1A1ALOX15TSHRPOLBL3MBTL1 | |
| SCHEMBL422 | 0.81 | ALDH1A1 (0.67) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL2402121 | 0.81 | ALDH1A1 (0.50) | ALDH1A1ALOX15TSHRHNF4AMYC | |
| SCHEMBL2153429 | 0.80 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL236867 | 0.80 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL5285030 | 0.80 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL893277 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL28422933 | 0.79 | ALDH1A1 (0.64) | ALDH1A1ALOX15TSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767825-B2 | 2,2′,6,6′-tetraoxazolinyl biphenyl ligand and method for preparing the same | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2010-08-03 | — | — | US | disclosed |
| US-7767825-B2 | 2,2′,6,6′-tetraoxazolinyl biphenyl ligand and method for preparing the same | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2010-08-03 | — | — | US | disclosed |
| US-20090043104-A1 | 2,2',6,6' - TETRAOXAZOLINYL BIPHENYL LIGAND AND METHOD FOR PREPARING THE SAME | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043104-A1 | 2,2',6,6' - TETRAOXAZOLINYL BIPHENYL LIGAND AND METHOD FOR PREPARING THE SAME | IP6K2, PIP4K2C, IP6K3 | ALDH1A1 4305/4885ALOX15 4532/4885TSHR 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.