Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 4/20 | 0.55 |
| ▸ | MTHFD1 | P11586 | 2/20 | 0.54 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.54 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.54 |
| ▸ | ATIC | P31939 | 4/20 | 0.51 |
| ▸ | GART | P22102 | 3/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrofolic Acid SCHEMBL2510798 | 1.00 | TYMS (0.56) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17548881 | 0.91 | TYMS (0.47) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Dihydrofolic Acid SCHEMBL12136386 | 0.87 | SOST (0.61) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Dihydrofolic Acid SCHEMBL27589172 | 0.87 | SOST (0.61) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Dihydrofolic Acid SCHEMBL8281 | 0.87 | SOST (0.61) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Dihydrofolic Acid SCHEMBL8282 | 0.87 | SOST (0.61) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Dihydrofolic Acid SCHEMBL27415499 | 0.87 | SOST (0.60) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Dihydrofolic Acid SCHEMBL27779274 | 0.86 | SOST (0.60) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL25796224 | 0.85 | DHFR (0.57) | TYMSDHFRMTHFD1MTHFD2ATIC | |
| 7,8-Dihydropteroate SCHEMBL609952 | 0.84 | TSHR (0.38) | TYMSKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2091 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022110-A1 | DIARYLACETYLENE COMPOUND, PREPARATION METHOD THEREOF, AND USES THEREOF | HENAN RADIOMEDICAL SCIENCE AND TECH CO LTD (CN) | 2026-01-22 | — | — | US | claimed |
| CN-120064485-A | LC-MS/MS-based method for determining one-carbon metabolic pathway substances in plasma sample | 武汉迈维代谢生物科技股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| US-12261197-B2 | Diffusion barrier layer in top electrode to increase break down voltage | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2025-03-25 | — | — | US | claimed |
| EP-4500182-A1 | PROGNOSTIC BIOMARKERS | The University of Liverpool (GB) | 2025-02-05 | — | — | EP | claimed |
| CN-119112866-A | Application of rotenone compounds in preparing medicament for treating psoriasis | 广州锐达致广医药科技有限公司 | 2024-12-13 | — | — | CN | claimed |
| US-20240358740-A1 | FOLIC COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC NEUROPATHIES | CROSS III WILLIAM H (US) | 2024-10-31 | — | — | US | claimed |
| WO-2024217219-A1 | DIARYLACETYLENE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 河南省锐达医药科技有限公司 | 2024-10-24 | — | — | WO | claimed |
| EP-4444898-A1 | PREDICTION, BIOSYNTHESIS, AND INTEGRATION AS BIOSENSORS OF MOLECULES WITH UNIQUE LIGHT ABSORBANCE SIGNATURES AND THEIR SUBSEQUENT IN-FIELD REMOTE DETECTION USING MULTI OR HYPER-SPECTRAL CAMERAS | Massachusetts Institute of Technology (US) | 2024-10-16 | — | — | EP | claimed |
| CN-115436502-B | Method for detecting concentration of folic acid and derivative thereof in blood plasma based on LC-MS/MS technology | 连云港金康和信药业有限公司 | 2024-07-30 | — | — | CN | claimed |
| US-12029750-B2 | Folic compositions and methods for treatment of diabetic neuropathies | CROSS III WILLIAM H (US) | 2024-07-09 | — | — | US | claimed |
| EP-0355189-B1 | PROCESS FOR THICKENING/DEWATERING SEWAGE SLUDGE | Blum, Holger (DE) | 1992-07-08 | — | — | EP | claimed |
| EP-0319598-B1 | STABILIZED AQUEOUS PREPARATION OF FOLIC ACID | Blum, Holger (DE) | 1991-09-25 | — | — | EP | claimed |
| US-4956092-A | Method for concentrating/dehydrating of sewage sludge | BLUM HOLGER (DE) | 1990-09-11 | — | — | US | claimed |
| EP-0179654-B1 | PROCESS FOR THE PREPARATION OF 5,6,7,8-TETRAHYDROFOLIC ACID | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-07-25 | — | — | EP | claimed |
| US-4931442-A | Stabilized aqueous folic acid preparation | BLUM HOLGER (DE) | 1990-06-05 | — | — | US | claimed |
| US-4929551-A | Process for producing L(-)-tetrahydrofolic acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-05-29 | — | — | US | claimed |
| EP-0356934-A2 | Process for producing L(-)tetrahydrofolic acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-03-07 | — | — | EP | claimed |
| US-4665176-A | CATALYTIC HYDROGENATION | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-05-12 | — | — | US | claimed |
| EP-0179654-A2 | Process for the preparation of 5,6,7,8-tetrahydrofolic acid | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-04-30 | — | — | EP | claimed |
| EP-0121399-A2 | A method for producing hybrids between myeloma cells and normal cells | BIO-RESPONSE INC. (US) | 1984-10-10 | — | — | EP | claimed |