Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KDM5C | P41229 | 4/20 | 0.45 |
| ▸ | KDM6B | O15054 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27394937 | 0.80 | CASP2 (0.47) | LMNAHTTL3MBTL1 | |
| SCHEMBL2442181 | 0.77 | PHF8 (0.48) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL3494897 | 0.76 | PHF8 (0.46) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL6866925 | 0.76 | PHF8 (0.46) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL23452547 | 0.75 | FAAH (0.59) | MAPK1EPHX2 | |
| SCHEMBL13202008 | 0.75 | SLC6A5 (0.38) | LMNA | |
| SCHEMBL24002296 | 0.75 | LMNA (0.44) | LMNAEPHX2L3MBTL1 | |
| SCHEMBL12120976 | 0.75 | — | — | |
| SCHEMBL6810784 | 0.73 | PHF8 (0.60) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL3968787 | 0.72 | FAAH (0.54) | PHF8KDM2AEGLN1KDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873879-B2 | Nucleic acid fragment binding to target protein | TAGCYX BIOTECHNOLOGIES (JP) | 2018-01-23 | — | — | US | disclosed |
| US-20170073683-A1 | NUCLEIC ACID FRAGMENT BINDING TO TARGET PROTEIN | TAGCYX BIOTECHNOLOGIES (JP) | 2017-03-16 | — | — | US | disclosed |
| US-9540650-B2 | Nucleic acid fragment binding to target protein | TAGCYX BIOTECHNOLOGIES (JP) | 2017-01-10 | — | — | US | disclosed |
| US-20150119254-A1 | NUCLEIC ACID FRAGMENT BINDING TO TARGET PROTEIN | TAGCYX BIOTECHNOLOGIES (JP) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119254-A1 | NUCLEIC ACID FRAGMENT BINDING TO TARGET PROTEIN | TARBP1, DNTT, FABP1 | PHF8 3058/4885KDM2A 4644/4885EGLN1 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.