Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13949817 | 0.83 | KDM4E (0.52) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL21695694 | 0.81 | KDM4E (0.68) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL31497564 | 0.79 | EPHX2 (0.62) | EPHX2CASP2FAAHNAAADNM1 | |
| SCHEMBL17371277 | 0.78 | FAAH (0.64) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL23452547 | 0.78 | FAAH (0.59) | MAPK1EPHX2CASP2FAAHNAAA | |
| SCHEMBL19960974 | 0.77 | CASP2 (0.71) | KDM4EMAPK1HIF1AADRA1AEPHX2 | |
| SCHEMBL16864576 | 0.77 | KDM4E (0.61) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL24067534 | 0.77 | ADRA1A (0.85) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL23735533 | 0.77 | KDM4E (0.61) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL13445262 | 0.77 | KDM4E (0.61) | KDM4EMAPK1HIF1AADRA1APAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196295-A1 | UV Excitable Fluorescent Energy Transfer Dyes | Life Technologies Corporation (US) | 2012-08-02 | — | — | US | disclosed |
| US-8129529-B2 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110077415-A1 | UV Excitable Fluorescent Energy Transfer Dyes | Life Technologies Corporation (US) | 2011-03-31 | — | — | US | disclosed |
| US-7888507-B2 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC | 2011-02-15 | — | — | US | disclosed |
| US-7550570-B2 | Labeling nucleotide sequences with rhodamine dye | APPLIED BIOSYSTEMS, LLC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-20090093623-A1 | 4,7-DICHLORORHODAMINE DYES | APPLIED BIOSYSTEMS INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090062543-A1 | UV EXCITABLE FLUORESCENT ENERGY TRANSFER DYES | APPLIED BIOSYSTEMS INC. (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090031506-A1 | UV Excitable Fluorescent Energy Transfer Dyes | APPLERA CORPORATION (US) | 2009-02-05 | — | — | US | disclosed |
| US-7402671-B2 | UV excitable fluorescent energy transfer dyes | APPLERA CORPORATION (US) | 2008-07-22 | — | — | US | disclosed |
| US-7378517-B2 | UV excitable energy transfer reagents | APPLERA CORPORATION (US) | 2008-05-27 | — | — | US | disclosed |
| US-7179906-B2 | Asymmetric benzoxanthene dyes | APPLERA CORPORATION (US) | 2007-02-20 | — | — | US | disclosed |
| US-7169939-B2 | Energy transfer dyes with enhanced fluorescence | APPLERA CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-7157572-B2 | UV excitable energy transfer reagents | APPLERA CORPORATION (US) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062543-A1 | UV EXCITABLE FLUORESCENT ENERGY TRANSFER DYES | SLC46A1, SLC43A3, SLC25A4 | KDM4E 3624/4885MAPK1 3417/4885HIF1A 3329/4885 |
| US-20090093623-A1 | 4,7-DICHLORORHODAMINE DYES | POLL, FPR3, DRD4 | KDM4E 1350/4885MAPK1 3651/4885HIF1A 2854/4885 |
| US-20120196295-A1 | UV Excitable Fluorescent Energy Transfer Dyes | SLC46A1, SLC43A3, SLC25A4 | KDM4E 3624/4885MAPK1 3417/4885HIF1A 3329/4885 |
| US-20110077415-A1 | UV Excitable Fluorescent Energy Transfer Dyes | SLC46A1, SLC43A3, SLC25A4 | KDM4E 3624/4885MAPK1 3417/4885HIF1A 3329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.