Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316004 | 0.84 | GABRA1 (0.46) | GABRA1GABRB2POLB | |
| SCHEMBL29951868 | 0.79 | NOTUM (0.40) | — | |
| SCHEMBL190968 | 0.77 | GABRA1 (0.52) | GABRA1GABRB2POLB | |
| SCHEMBL846677 | 0.77 | GABRA1 (0.46) | GABRA1GABRB2POLB | |
| SCHEMBL13208363 | 0.75 | GABRA1 (0.33) | GABRA1GABRB2POLB | |
| SCHEMBL13208354 | 0.75 | GABRA1 (0.33) | GABRA1GABRB2POLB | |
| SCHEMBL28241863 | 0.74 | GABRA1 (0.50) | GABRA1GABRB2POLB | |
| SCHEMBL12400058 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL31071024 | 0.70 | RXRB (0.41) | GABRA1GABRB2POLB | |
| SCHEMBL23915436 | 0.69 | GABRA1 (0.44) | GABRA1GABRB2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197657-A1 | 2-ARYL OR HETEROARYL INDOLE DERIVATIVES | CHANG RONALD K | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197657-A1 | 2-ARYL OR HETEROARYL INDOLE DERIVATIVES | ASIC1, ASIC3, TRPV1 | GABRA1 266/4885GABRB2 184/4885POLB 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.