SCHEMBL132133

SCHEMBL132133

Pc1c(-c2ccccc2)c(-c2ccccc2)cc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
RECQL P46063 1/20 0.47
KDM4E B2RXH2 4/20 0.47
HPGD P15428 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 1/20 0.47
MPI P34949 1/20 0.47
GPR84 Q9NQS5 6/20 0.46
ALOX5 P09917 1/20 0.45
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
CYP11B1 P15538 1/20 0.40
LMNA P02545 1/20 0.39
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1408488 0.86 GPR84 (0.51) MEN1KMT2ARECQLKDM4EHPGD
SCHEMBL15661189 0.83 MEN1 (0.41) MEN1KMT2ARECQLKDM4EHPGD
SCHEMBL31756884 0.82 GPR84 (0.54) MEN1KMT2ARECQLKDM4EHPGD
SCHEMBL4780472 0.82 GPR84 (0.54) MEN1KMT2ARECQLKDM4EHPGD
SCHEMBL15660329 0.80 MEN1 (0.39) MEN1KMT2ARECQLKDM4EHPGD
SCHEMBL10933586 0.79 BACE1 (0.44) MEN1KMT2AKDM4EHPGDALDH1A1
SCHEMBL30902294 0.77 MEN1 (0.47) MEN1KMT2ARECQLKDM4EHPGD
SCHEMBL11758656 0.77 MEN1 (0.47) MEN1KMT2ARECQLKDM4EHPGD
SCHEMBL2494553 0.77 MEN1 (0.51) MEN1KMT2ARECQLKDM4EHPGD
SCHEMBL272956 0.77 MEN1 (0.47) MEN1KMT2ARECQLKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111689847-B Preparation method of aryl propionic acid compound 浙江新和成股份有限公司 2022-05-17 CN claimed
CN-111689847-A Preparation method of aryl propionic acid compound 浙江新和成股份有限公司 2020-09-22 CN claimed
WO-2018147793-A1 CARBONYLATION PROCESS AND LIGAND COMPOSITION COMPRISING A BIDENTATE PHOSPHITE LIGAND AND A TERTIARY PHOSPHINE ANTI-OXIDANT PERSTORP AB (SE) 2018-08-16 WO claimed
US-12534590-B2 Recycle content cyclobutane diol polyester EASTMAN CHEMICAL COMPANY (US) 2026-01-27 US disclosed
US-20250289782-A1 THIOL COMPOUND AND USES THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2025-09-18 US disclosed
EP-4004081-B1 RECYCLE CONTENT CYCLOBUTANE DIOL POLYESTER EASTMAN CHEM CO (US) 2025-09-17 EP disclosed
US-20250276949-A1 RECYCLE CONTENT (C4)ALKANAL EASTMAN CHEMICAL COMPANY (US) 2025-09-04 US disclosed
US-12338211-B2 Recycle content (C4)alkanal EASTMAN CHEMICAL COMPANY (US) 2025-06-24 US disclosed
WO-2025100238-A1 EPOXY COMPOUND AND USE THEREOF 四国化成工業株式会社 2025-05-15 WO disclosed
EP-4524174-A1 CURING AGENT AND USE THEREOF Shikoku Chemicals Corporation (JP) 2025-03-19 EP disclosed
EP-4524130-A1 THIOL COMPOUND AND USES THEREOF Shikoku Chemicals Corporation (JP) 2025-03-19 EP disclosed
WO-1996022265-A1 HYDROFORMYLATION PROCESS EXXON CHEMICAL LIMITED (GB) 1996-07-25 WO disclosed
WO-1996022266-A1 HYDROFORMYLATION OF A MULTI-COMPONENT FEED STREAM EXXON RESEARCH & ENGINEERING COMPANY (US) 1996-07-25 WO disclosed
WO-1996022268-A1 ORGANIC COMPOUNDS AND PROCESSES FOR THEIR MANUFACTURE EXXON CHEMICAL PATENTS INC. (US) 1996-07-25 WO disclosed
US-5342929-A Direct glycosylation leads to the desired glycosides in high yield and relatively short reaction times using metal complex salts; large amounts of the alpha- or beta-form are often obtained CIBA-GEIGY CORPORATION (US) 1994-08-30 US disclosed
EP-0016286-B1 HYDROFORMYLATION PROCESS DAVY McKEE (LONDON) LIMITED (GB) 1983-04-06 EP disclosed
US-4287370-A BY HYDROFORMYLATION OF 1-BUTENE IN THE PRESENCE OF A COMPLEX CATALYST OF RHODIUM, CARBON MONOXIDE AND A TRIORGANOPHOSPHINE DAVY MCKEE (OIL & CHEMICALS) LIMITED (GB) 1981-09-01 US disclosed
EP-0016286-A2 Hydroformylation process DAVY McKEE (LONDON) LIMITED (GB) 1980-10-01 EP disclosed
US-4188274-A DECARBOXYLATION STANDARD OIL COMPANY (INDIANA) (US) 1980-02-12 US disclosed
US-4174447-A SILVER SALTS OF CARBOXY ACIDS STANDARD OIL COMPANY (INDIANA) (US) 1979-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289782-A1 THIOL COMPOUND AND USES THEREOF TMT1A, TXN, CTH MEN1 4846/4885KMT2A 1016/4885RECQL 4251/4885
US-12534590-B2 Recycle content cyclobutane diol polyester PGD, MCCC2, PCCA MEN1 2523/4885KMT2A 4772/4885RECQL 2966/4885
US-12338211-B2 Recycle content (C4)alkanal ALKBH3, AKR1C4, CBR1 MEN1 3929/4885KMT2A 3313/4885RECQL 824/4885
US-20250276949-A1 RECYCLE CONTENT (C4)ALKANAL ALKBH3, AKR1C4, CBR1 MEN1 3929/4885KMT2A 3313/4885RECQL 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.