Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 7/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 6/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595684 | 1.00 | CYP3A4 (1.00) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL7235093 | 0.85 | CYP3A4 (0.73) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL28084040 | 0.83 | CYP3A4 (0.71) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL820508 | 0.82 | CYP3A4 (0.70) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL31408101 | 0.80 | IDO1 (0.73) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL16382293 | 0.80 | IDO1 (0.73) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL27768062 | 0.79 | CYP3A4 (0.66) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL28484926 | 0.77 | IDO1 (0.63) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL12017706 | 0.77 | CYP1A2 (0.62) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL994454 | 0.77 | CYP1A2 (0.62) | CYP3A4CYP2D6CYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260083844-A1 | DOWNREGULATING INOS TO INCREASE CAR-T KILLING | H LEE MOFFITT CANCER CT & RES (US) | 2026-03-26 | — | — | US | claimed |
| US-12194448-B2 | Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same | THE GEORGE WASHINGTON UNIVERSITY (US) | 2025-01-14 | — | — | US | claimed |
| WO-2024224296-A2 | TARGETED PHARMACEUTICAL COMPOSITIONS TO TREAT NEUROLOGICAL CONDITIONS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-10-31 | — | — | WO | claimed |
| WO-2024059834-A2 | DOWNREGULATING INOS TO INCREASE CAR-T KILLING | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC. (US) | 2024-03-21 | — | — | WO | claimed |
| CN-116685302-A | Topical compositions | 利勒格有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-114437407-A | Vulcanized composition, EPDM-based vulcanized rubber composition, vulcanized rubber, and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| US-20200171474-A1 | CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME | THE GEORGE WASHINGTON UNIVERSITY | 2020-06-04 | — | — | US | claimed |
| WO-2018213821-A1 | CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME | THE GEORGE WASHINGTON UNIVERSITY (US) | 2018-11-22 | — | — | WO | claimed |
| US-20140031289-A1 | POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-01-30 | — | — | US | claimed |
| US-20090186929-A1 | Method and agent for inducing apoptosis/cell death in leukemia cells | U.S. DEPARTMENT OF VETERANS AFFAIRS (US) | 2009-07-23 | — | — | US | claimed |
| US-20050234026-A1 | Method and agent for inducing apoptosis/cell death in leukemia cells | VETERANS AFFAIRS, U.S. DEPARTMENT OF | 2005-10-20 | — | — | US | claimed |
| WO-2005046660-A1 | MODULATING SUBSTANCES OF THE NITRIC OXID (NO) - CYCLIC GUANOSINE - 3’,5’- MONOPHOSPHATE (cGMP) SIGNALING PATHWAY FOR THE TREATMENT OF DENTAL DISORDERS | CELL CENTER COLOGNE GMBH (DE) | 2005-05-26 | — | — | WO | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| EP-1280526-A1 | COMPOSITION FOR THE PREVENTION AND/OR TREATMENT, IN NEWBORN BABIES, OF THE EFFECTS OF COMPLICATIONS DURING CHILDBIRTH | Universitair Medisch Centrum Utrecht (NL) | 2003-02-05 | — | — | EP | claimed |
| US-20020156129-A1 | Method of treating pruritus and a pharmaceutical composition for the method | IKEDA MOHANDO CO., LTD. (JP) | 2002-10-24 | — | — | US | claimed |
| WO-2002069910-A2 | USE OF SUBSTANCES THAT PREVENT THAT THE NO SYNTHASE OF WARM-BLOODED ORGANISMS TAKES EFFECT, FOR PRODUCING COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR THE TREATMENT AND/OR THE PROPHYLAXIS OF UNDESIRED SKIN PIGMENTATION | BEIERSDORF AG (DE) | 2002-09-12 | — | — | WO | claimed |
| WO-2001074351-A1 | COMPOSITION FOR THE PREVENTION AND/OR TREATMENT, IN NEWBORN BABIES, OF THE EFFECTS OF COMPLICATIONS DURING CHILDBIRTH | UNIVERSITAIR MEDISCH CENTRUM (NL) | 2001-10-11 | — | — | WO | claimed |
| WO-2000061126-A2 | METHOD OF TREATING NEUROLOGICAL DISORDERS WITH COMBINATIONS OF NITRIC OXIDE SYNTHASE INHIBITORS AND EXCITATORY AMINO ACID RECEPTOR MODULATORS | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-19 | — | — | WO | claimed |
| CN-122048632-A | Tone adjustment method, tone adjustment device, electronic apparatus, and storage medium | 北京达佳互联信息技术有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-4431815-A | CARDIOTONIC AND ANTISHOCK AGENTS; ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1984-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260083844-A1 | DOWNREGULATING INOS TO INCREASE CAR-T KILLING | NOS2, NOS1, NOS3 | CYP3A4 1266/4885CYP2D6 1508/4885CYP1A2 371/4885 |
| US-12194448-B2 | Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same | MLX, LDHA, CA2 | CYP3A4 3701/4885CYP2D6 3925/4885CYP1A2 3498/4885 |
| US-20140031289-A1 | POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF | PHOSPHO1, PLCB3, INPP5D | CYP3A4 395/4885CYP2D6 1588/4885CYP1A2 1936/4885 |
| US-20200171474-A1 | CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME | MLX, LDHA, CA2 | CYP3A4 3701/4885CYP2D6 3925/4885CYP1A2 3498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.