SCHEMBL8121

SCHEMBL8121

CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)n1cccn1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.32
ELANE P08246 1/20 0.32
PCSK9 Q8NBP7 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
NOS1 P29475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13221 1.00 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL14135 1.00 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL2343819 0.89 ELANE (0.35) ELANENOS1
SCHEMBL17560519 0.89 ELANE (0.35) ELANENOS1
SCHEMBL17654422 0.89 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL2127300 0.89 ELANE (0.35) ELANENOS1
SCHEMBL13518677 0.89 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL13518680 0.89 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL25504021 0.89 ELANE (0.32) ELANENOS1
SCHEMBL24177802 0.89 PCSK9 (0.33) ELANEPCSK9NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10155009-B2 Polyion complex of poly(L-arginine) segment-containing block copolymer and polyanionic polymer General Incorporated Association Tsukuba Global Innovation Promotion Agency (JP) 2018-12-18 US claimed
US-20180085395-A1 POLYION COMPLEX OF POLY(L-ARGININE) SEGMENT-CONTAINING BLOCK COPOLYMER AND POLYANIONIC POLYMER General Incorporated Association Tsukuba Global Innovation Promotion Agency (JP) 2018-03-29 US claimed
EP-3284474-A1 POLYION COMPLEX OF POLY(L-ARGININE) SEGMENT-CONTAINING BLOCK COPOLYMER AND POLYANIONIC POLYMER General Incorporated Association Tsukuba Global Innovation Promotion Agency (JP) 2018-02-21 EP claimed
US-20150368192-A1 A METHOD OF SYNTHESIZING CREATINE DERIVATIVES UNIV DEGLI STUDI GENOVA (IT) 2015-12-24 US claimed
EP-2935207-A1 A METHOD OF SYNTHESIZING CREATINE DERIVATIVES Universita' degli Studi di Genova (IT) 2015-10-28 EP claimed
WO-2014097335-A1 A METHOD OF SYNTHESIZING CREATINE DERIVATIVES UNIVERSITA' DEGLI STUDI DI GENOVA (IT) 2014-06-26 WO claimed
US-20050090525-A1 Isoquinoline derivatives MERCK PATENT GMBH (DE) 2005-04-28 US claimed
CN-122055148-A Conjugates, compositions and methods for treating influenza 珀杜研究基金会 2026-05-15 CN disclosed
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2026-04-23 US disclosed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
US-12569565-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2026-03-10 US disclosed
WO-2026044019-A1 COMPOSITIONS AND METHODS FOR TREATING INFLUENZA INFECTION LOW STEWART (US) 2026-02-26 WO disclosed
US-5714606-A OLIGONUCLEOTIDE HAVING RECEPTOR BINDING SITES; ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS, MEDICAL DIAGNOSIS ISIS PHARMACEUTICALS, INC. (US) 1998-02-03 US disclosed
WO-1997011693-A1 GUANIDINO PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1997-04-03 WO disclosed
EP-0759917-A1 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES GILEAD SCIENCES, INC. (US) 1997-03-05 EP disclosed
WO-1997006157-A1 DIHYDROPYRAN DERIVATIVES AS VIRAL NEURAMINIDASE INHIBITORS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 1997-02-20 WO disclosed
WO-1996026933-A9 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES 1996-11-28 WO disclosed
WO-1996036628-A1 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 1996-11-21 WO disclosed
WO-1996026933-A1 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES GILEAD SCIENCES, INC. (US) 1996-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368192-A1 A METHOD OF SYNTHESIZING CREATINE DERIVATIVES CKMT1A; CKMT1B, TNNI3, TNNT2 RAB9A 2597/4885ELANE 4385/4885PCSK9 1504/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 RAB9A 229/4885ELANE 1895/4885PCSK9 2183/4885
US-20050090525-A1 Isoquinoline derivatives ITGB1, ITGB3, ITGA1 RAB9A 1356/4885ELANE 1459/4885PCSK9 273/4885
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, FCGR1A, FCGR2A RAB9A 2594/4885ELANE 360/4885PCSK9 1978/4885
US-12569565-B2 Compositions and methods for the treatment of viral infections ALB, FCGR3B, FCGR1A RAB9A 1938/4885ELANE 183/4885PCSK9 1174/4885
US-10155009-B2 Polyion complex of poly(L-arginine) segment-containing block copolymer and polyanionic polymer ARG1, NOS2, ARG2 RAB9A 4637/4885ELANE 2025/4885PCSK9 4231/4885
US-20180085395-A1 POLYION COMPLEX OF POLY(L-ARGININE) SEGMENT-CONTAINING BLOCK COPOLYMER AND POLYANIONIC POLYMER ARG1, NOS2, ARG2 RAB9A 4637/4885ELANE 2025/4885PCSK9 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.