Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 4/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45857 | 0.77 | CCR1 (0.46) | NPSR1KDM4ERAB9ALMNAPOLB | |
| SCHEMBL13222357 | 0.77 | LTA4H (0.50) | NPSR1KDM4EHPGDSRAB9ALMNA | |
| SCHEMBL13114689 | 0.77 | CCR1 (0.56) | KDM4EHPGDSCCNCCDK8RAB9A | |
| SCHEMBL1558150 | 0.73 | CA2 (0.40) | KDM4EHPGDSCCNCCDK8CASP3 | |
| SCHEMBL30753608 | 0.73 | HPGDS (0.40) | HPGDSCCNCCDK8RAB9AL3MBTL1 | |
| SCHEMBL14988353 | 0.73 | HPGDS (0.40) | HPGDSCCNCCDK8RAB9AL3MBTL1 | |
| SCHEMBL31255994 | 0.73 | HPGDS (0.40) | HPGDSCCNCCDK8LTA4HBRD4 | |
| SCHEMBL7429910 | 0.73 | HPGDS (0.40) | HPGDSCCNCCDK8LTA4HBRD4 | |
| SCHEMBL29843360 | 0.73 | CA2 (0.40) | KDM4EHPGDSCCNCCDK8CASP3 | |
| SCHEMBL14211873 | 0.72 | HPGDS (0.37) | HPGDSCCNCCDK8LTA4HBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772183-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-08-10 | — | — | US | disclosed |
| US-20070093414-A1 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093414-A1 | Hepatitis C virus inhibitors | HAVCR2, HCCS, PYGL | NPSR1 4210/4885KDM4E 3825/4885HPGDS 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.