Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.64 |
| ▸ | CES1 | P23141 | 8/20 | 0.64 |
| ▸ | CES2 | O00748 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 5/20 | 0.54 |
| ▸ | PPARD | Q03181 | 5/20 | 0.54 |
| ▸ | PPARA | Q07869 | 5/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519725 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL3411867 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL8898693 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL9437438 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL8824699 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL23052919 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL16186191 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL16186192 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL22525240 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL16186190 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066113-A1 | MESSENGER RNA VACCINES AGAINST WIDE SPECTRUM OF CORONAVIRUS VARIANTS | ACADEMIA SINICA (TW) | 2024-02-29 | — | — | US | disclosed |
| US-20210177981-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED INSULIN DELIVERY | MERCK SHARP & DOHME CORP. (US) | 2021-06-17 | — | — | US | disclosed |
| WO-2021068464-A1 | HEAT-NOT-BURN VAPOR GENERATING BODY AND PREPARATION METHOD THEREFOR, TOBACCO PRODUCT AND VAPOR GENERATING BODY | 科巴特(深圳)生活科技有限公司 | 2021-04-15 | — | — | WO | disclosed |
| US-20150337013-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | MERCK SHARP & DOHME CORP. (US) | 2015-11-26 | — | — | US | disclosed |
| US-20140073558-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CUBIST PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-8507647-B2 | Antibacterial agents for the treatment of gram positive infections | CUBIST PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20100184649-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CUBIST PHARMACEUTICALS, INC. | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210177981-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED INSULIN DELIVERY | GPR119, INSR, IGF1R | FAAH 541/4885CES1 92/4885CES2 111/4885 |
| US-20150337013-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CLPP, CLPTM1, RPN1 | FAAH 1153/4885CES1 2802/4885CES2 3242/4885 |
| US-20100184649-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CLPP, CLPTM1, RPN1 | FAAH 1153/4885CES1 2802/4885CES2 3242/4885 |
| US-20240066113-A1 | MESSENGER RNA VACCINES AGAINST WIDE SPECTRUM OF CORONAVIRUS VARIANTS | SARNP, RNGTT, RBM3 | FAAH 2023/4885CES1 572/4885CES2 3437/4885 |
| US-20140073558-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CLPP, CLPTM1, RPN1 | FAAH 1153/4885CES1 2802/4885CES2 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.