Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCK1 | P35558 | 6/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247656 | 0.92 | PCK1 (0.47) | PCK1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL13248182 | 0.89 | PCK1 (0.49) | PCK1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL13248234 | 0.89 | ADORA1 (0.45) | ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL13248177 | 0.87 | ALDH1A1 (0.44) | ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL13247663 | 0.86 | ADORA1 (0.45) | ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL13248238 | 0.86 | ADORA3 (0.43) | ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL13247860 | 0.85 | PCK1 (0.53) | PCK1ADORA1ADORA2BADORA2A | |
| SCHEMBL13248236 | 0.85 | ADORA3 (0.43) | ADORA3ADORA1ADORA2BADORA2ACNR2 | |
| SCHEMBL13248176 | 0.85 | RXFP1 (0.46) | PCK1ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL13247653 | 0.84 | ADORA1 (0.53) | ADORA3ADORA1ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION | 2010-07-15 | — | — | US | disclosed |
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | XDH, GPR84, GPR88 | PCK1 2050/4885ADORA3 61/4885ADORA1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.