Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301 | 0.98 | CA1 (0.36) | CA1CA2CA7CA4CA9 | |
| SCHEMBL5335617 | 0.96 | CA1 (0.35) | CA1CA2CA7CA4CA9 | |
| Methylamine SCHEMBL28169634 | 0.93 | CA1 (0.35) | CA1CA2CA7CA4CA9 | |
| SCHEMBL27785265 | 0.84 | LMNA (0.38) | — | |
| SCHEMBL19260834 | 0.84 | CA1 (0.36) | CA1CA2CA7CA4CA9 | |
| SCHEMBL14780432 | 0.83 | CA1 (0.33) | CA1CA2CA7CA4CA9 | |
| SCHEMBL6663669 | 0.82 | LMNA (0.40) | — | |
| SCHEMBL20526044 | 0.78 | CA2 (0.37) | CA1CA2CA7CA9 | |
| SCHEMBL4445894 | 0.78 | CA1 (0.33) | CA1CA2CA7CA4CA9 | |
| SCHEMBL27751400 | 0.78 | CA1 (0.55) | CA1CA2CA7CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2019-06-13 | — | — | US | disclosed |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX INC (US) | 2018-09-27 | — | — | US | disclosed |
| EP-3356356-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| US-9732071-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2017-04-06 | — | — | US | disclosed |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | SENOMYX INC (US) | 2017-03-30 | — | — | US | disclosed |
| EP-1971316-B1 | PERSONAL CARE COMPOSITIONS CONTAINING CATIONICALLY MODIFIED STARCH AND AN ANIONIC SURFACTANT SYSTEM | PROCTER & GAMBLE (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| WO-2000000170-A1 | HAIR SHAMPOO AND CONDITIONER SYSTEM | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |
| WO-1999018929-A9 | PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | PROCTER & GAMBLE (US) | 1999-08-26 | — | — | WO | disclosed |
| WO-1999018928-A1 | PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999018929-A1 | PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| EP-0807161-A1 | IMPROVED PERSONAL CLEANSING BAR WITH TAILORED FATTY ACID SOAP | THE PROCTER & GAMBLE COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023863-A1 | IMPROVED PERSONAL CLEANSING BAR WITH TAILORED FATTY ACID SOAP | THE PROCTER & GAMBLE COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
| US-5540852-A | FATTY ACID SOAP MIXTURES | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0196824-A2 | Hair care compositions | THE PROCTER & GAMBLE COMPANY (US) | 1986-10-08 | — | — | EP | disclosed |
| EP-0158481-A2 | Hair care compositions | THE PROCTER & GAMBLE COMPANY (US) | 1985-10-16 | — | — | EP | disclosed |
| US-4198209-A | AMMONIUM PERCHLORATE, LEACHING WITH AN AQUEOUS SOLUTION CONTAINING A SURFACTANT | MCINTOSH MELDON J | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | CA1 3404/4885CA2 3081/4885CA7 3595/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | CA1 1069/4885CA2 375/4885CA7 2085/4885 |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | CA1 934/4885CA2 305/4885CA7 2328/4885 |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | CA1 934/4885CA2 305/4885CA7 2328/4885 |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | TRPA1, PDE6G, PDE6D | CA1 2228/4885CA2 581/4885CA7 688/4885 |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | CA1 934/4885CA2 305/4885CA7 2328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.