Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 8/20 | 0.49 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257678 | 0.93 | PDE11A (0.43) | APLNRPDE11APDE7AMAPTTP53 | |
| SCHEMBL13257642 | 0.90 | PDE7A (0.51) | PDE7ATSHRMAPTTP53LMNA | |
| SCHEMBL13257600 | 0.86 | MAPT (0.37) | APLNRPDE7ATSHRMAPTTP53 | |
| SCHEMBL13257531 | 0.84 | LMNA (0.44) | PDE7ALMNAMAPK1CYP2C19 | |
| SCHEMBL13257621 | 0.82 | APLNR (0.48) | APLNRPDE11APDE7ATSHRMAPT | |
| SCHEMBL13258437 | 0.82 | PDE7A (0.40) | PDE7AMAPTTP53LMNAUSP2 | |
| SCHEMBL13257504 | 0.82 | SMN1; SMN2 (0.37) | APLNRMAPTTP53MAPK1USP2 | |
| SCHEMBL2565059 | 0.82 | FADS1 (0.54) | APLNRPDE11APDE7ATSHRMAPT | |
| SCHEMBL13257538 | 0.81 | PDE7A (0.49) | PDE7ATSHRMAPTTP53LMNA | |
| SCHEMBL13257463 | 0.77 | ALDH1A1 (0.35) | PDE7ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |