Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257642 | 0.83 | PDE7A (0.51) | PDE7AALDH1A1HTTTGM2LMNA | |
| SCHEMBL2559383 | 0.83 | FADS1 (0.46) | PDE7AALDH1A1HTTTP53TSHR | |
| SCHEMBL13257463 | 0.82 | ALDH1A1 (0.35) | PDE7AALDH1A1HTTTGM2PABPC1 | |
| SCHEMBL13257534 | 0.81 | APLNR (0.49) | PDE7ALMNATP53MAPTTSHR | |
| SCHEMBL13258437 | 0.81 | PDE7A (0.40) | PDE7AALDH1A1HTTTGM2LMNA | |
| SCHEMBL13257678 | 0.80 | PDE11A (0.43) | PDE7ALMNATP53MAPTUSP2 | |
| SCHEMBL13257531 | 0.79 | LMNA (0.44) | PDE7AALDH1A1LMNA | |
| SCHEMBL13258448 | 0.77 | JAK1 (0.37) | — | |
| SCHEMBL2566638 | 0.77 | TSHR (0.46) | PDE7AALDH1A1LMNATP53MAPT | |
| SCHEMBL13257504 | 0.76 | SMN1; SMN2 (0.37) | ALDH1A1TGM2TP53MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |