Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 11/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15501063 | 0.65 | HIF1A (0.51) | HIF1AEPAS1ALDH1A1FBP1MAPK1 | |
| SCHEMBL29520661 | 0.60 | HIF1A (1.00) | HIF1AEPAS1 | |
| Rhodomyrtoxin SCHEMBL12210330 | 0.57 | FBP1 (0.49) | HIF1AEPAS1FBP1MAPK1BCL2L1 | |
| SCHEMBL14645012 | 0.57 | FBP1 (0.46) | HIF1AEPAS1FBP1MAPK1BCL2L1 | |
| Isodispar B SCHEMBL29516983 | 0.56 | HIF1A (0.64) | HIF1AEPAS1ALDH1A1HPGDKDM4E | |
| SCHEMBL11861985 | 0.54 | KDM4E (0.58) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL504402 | 0.53 | MEN1 (0.55) | HIF1AEPAS1FBP1MAPK1BCL2L1 | |
| SCHEMBL7221645 | 0.53 | ELANE (0.58) | ALDH1A1KDM4EFBP1RAB9AGAA | |
| SCHEMBL7028753 | 0.53 | HIF1A (0.52) | HIF1AEPAS1ALDH1A1HPGDKDM4E | |
| SCHEMBL11895218 | 0.52 | FFAR1 (0.55) | ALDH1A1HPGDKDM4EFBP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216335-A1 | TETRIACYCLODIPYRANYL COUMARINS AND THE ANTI-HIV AND ANTI-TUBERCULOSIS USES THEREOF | Institute of Mataria Medica, Chinese Academy of Medical Sciences (CN) | 2010-08-11 | — | — | EP | disclosed |