Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14537709 | 0.82 | HPGD (0.51) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL13265711 | 0.80 | HPGD (0.50) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL13265822 | 0.79 | LMNA (0.58) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL13265966 | 0.77 | KMT2A (0.58) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL13265972 | 0.74 | ALPL (0.65) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL12190245 | 0.74 | MMP1 (0.54) | MAPTMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL13265857 | 0.73 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL16023929 | 0.73 | ALDH1A1 (0.59) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13265815 | 0.73 | AMY1A (0.54) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13265971 | 0.72 | L3MBTL1 (0.63) | MAPTMEN1KMT2AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754773-B2 | Composition and synthesis of new reagents for inhibition of HIV replication | UNIVERSITY OF MASSACHUSETTS (US) | 2010-07-13 | — | — | US | disclosed |