Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MYD88 | Q99836 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25383394 | 0.83 | KMT2A (0.63) | KMT2AALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL13265839 | 0.81 | KMT2A (0.49) | KMT2AALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL13265681 | 0.81 | KMT2A (0.60) | KMT2AALDH1A1MEN1ARLMNA | |
| SCHEMBL13265689 | 0.80 | ALDH1A1 (0.55) | KMT2AALDH1A1MEN1ARLMNA | |
| SCHEMBL13265932 | 0.78 | KMT2A (0.62) | KMT2AALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL14537875 | 0.76 | DDX3X (0.57) | KMT2AALDH1A1MEN1KDM4EKDM1A | |
| SCHEMBL14537878 | 0.75 | L3MBTL1 (0.51) | KMT2AALDH1A1MEN1LMNAL3MBTL1 | |
| SCHEMBL26005944 | 0.74 | POLB (0.57) | KMT2AALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL9517147 | 0.72 | PGR (0.54) | KMT2AMEN1LMNAPGRMAPT | |
| SCHEMBL13970848 | 0.71 | ALDH1A1 (0.71) | KMT2AALDH1A1MEN1KDM4EAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754773-B2 | Composition and synthesis of new reagents for inhibition of HIV replication | UNIVERSITY OF MASSACHUSETTS (US) | 2010-07-13 | — | — | US | disclosed |