Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265928 | 0.81 | DDX3X (0.57) | DDX3XKMT2AMAPTKDM4ECYTH2 | |
| SCHEMBL13265924 | 0.76 | KMT2A (0.58) | KMT2AMAPTKDM4ENFKBIARELA | |
| SCHEMBL14537878 | 0.76 | L3MBTL1 (0.51) | KMT2AMAPTCYP19A1ALDH1A1GAA | |
| SCHEMBL13265681 | 0.75 | KMT2A (0.60) | KMT2AMAPTCYP19A1ALDH1A1MEN1 | |
| SCHEMBL13265689 | 0.74 | ALDH1A1 (0.55) | KMT2AMAPTCYP19A1KDM1AMAOA | |
| SCHEMBL13265932 | 0.74 | KMT2A (0.62) | KMT2AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL7176595 | 0.73 | ALDH1A1 (0.66) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL11863940 | 0.73 | DDX3X (1.00) | DDX3XKMT2AMAPTKDM4ENFKBIA | |
| SCHEMBL23057254 | 0.72 | GAA (0.59) | DDX3XKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL18023815 | 0.72 | DDX3X (0.74) | DDX3XKMT2AMAPTKDM4ECYTH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099919-A1 | Composition and synthesis of new reagents for inhibition of HIV replication | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099919-A1 | Composition and synthesis of new reagents for inhibition of HIV replication | REV1, MAVS, ISG15 | DDX3X 322/4885KMT2A 1930/4885MAPT 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.