Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780892 | 0.83 | CNR2 (0.44) | CNR2POLBALDH1A1ANPEPL3MBTL1 | |
| SCHEMBL2784556 | 0.78 | PKM (0.41) | CNR2POLBALDH1A1L3MBTL1LMNA | |
| SCHEMBL13196604 | 0.78 | CNR2 (0.40) | CNR2POLBALDH1A1ANPEPL3MBTL1 | |
| SCHEMBL2783111 | 0.76 | POLB (0.48) | CNR2POLBALDH1A1ANPEPKDM4E | |
| SCHEMBL13196442 | 0.76 | ALDH1A1 (0.41) | CNR2POLBALDH1A1ANPEPL3MBTL1 | |
| SCHEMBL13196436 | 0.76 | POLB (0.45) | POLBALDH1A1ANPEPL3MBTL1KDM4E | |
| SCHEMBL2780358 | 0.75 | CNR2 (0.39) | CNR2POLBALDH1A1ANPEPL3MBTL1 | |
| SCHEMBL2782395 | 0.75 | HTT (0.39) | CNR2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL3467433 | 0.74 | KMT2A (0.49) | CNR2POLBMEN1KMT2AKDM4E | |
| SCHEMBL13196558 | 0.74 | NAMPT (0.39) | CNR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | disclosed |