Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804382 | 0.74 | MEN1 (0.32) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL1808770 | 0.68 | MEN1 (0.45) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL21643711 | 0.68 | MEN1 (0.45) | MEN1ALDH1A1KMT2ATDP1 | |
| Tetrachlorothiophene SCHEMBL433499 | 0.67 | — | — | |
| SCHEMBL8136097 | 0.67 | — | — | |
| SCHEMBL1586521 | 0.66 | GLA (0.35) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL13064760 | 0.65 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL4658299 | 0.65 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL12123971 | 0.63 | MEN1 (0.32) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL1811779 | 0.63 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486986-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-16 | — | — | US | disclosed |
| US-8486986-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-16 | — | — | US | disclosed |
| EP-2379536-B1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| US-8357635-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-01-22 | — | — | US | disclosed |
| US-8273783-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-25 | — | — | US | disclosed |
| EP-2488501-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202867-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-09 | — | — | US | disclosed |
| US-8202894-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2012-06-19 | — | — | US | disclosed |
| US-8202894-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2012-06-19 | — | — | US | disclosed |
| US-20110281924-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-17 | — | — | US | disclosed |
| EP-2379536-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2011-10-26 | — | — | EP | disclosed |
| WO-2011045355-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-04-21 | — | — | WO | disclosed |
| US-20100227898-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100222389-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100222389-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| WO-2010084078-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-07-29 | — | — | WO | disclosed |
| WO-2009003672-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-08 | — | — | WO | disclosed |
| WO-2008151828-A2 | NOVEL MICROBIOCIDES | SYNGETA PARTICIPATIONS AG (CH) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227898-A1 | NOVEL MICROBIOCIDES | FPR1, CD14, MSR1 | MEN1 2778/4885ALDH1A1 419/4885KMT2A 4239/4885 |
| US-20110281924-A1 | NOVEL MICROBIOCIDES | CD14, FPR1, MPO | MEN1 3185/4885ALDH1A1 433/4885KMT2A 4264/4885 |
| US-20100222389-A1 | NOVEL MICROBIOCIDES | CD14, FPR1, MPO | MEN1 2971/4885ALDH1A1 485/4885KMT2A 4273/4885 |
| US-20120202867-A1 | NOVEL MICROBIOCIDES | CD14, FPR1, MPO | MEN1 3185/4885ALDH1A1 433/4885KMT2A 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.